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6482 ST3GAL1

6482

ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition ST3 beta-galactoside alpha-2,3-sialyltransferase 1

研究结论

Date Results Publications
2020-12-19 13:45:00 ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL. 33203881
2020-11-21 13:20:00 Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1). 31784620
2019-12-14 11:45:00 ST3GAL1 promotes cell migration, invasion, and TGFB1-induced epithelial-mesenchymal transition and confers paclitaxel resistance in ovarian cancer. 30375371
2019-10-05 11:48:00 Data suggest that GDNF family receptor alpha 1 protein (GFRA1) is a protein target of ST3 beta-galactoside alpha-23-sialyltransferase 1 (ST3GAL1). 30040982
2019-07-13 11:49:00 Expression levels of ST3Gal1 and TGFB1 were high in breast cancer tumors samples and positively correlated with each other. Shorter relapse-free survival associated with lower expression of VASN and combination of low VASN with high ST3GAL1 yielded even higher risk of recurrence. Findings illustrated a feedback regulatory loop in which TGF-beta1 upregulates ST3Gal1 to circumvent the negative impact of VASN. 30252131

名称对应

Type IDs
Synonymous Gal-NAc6S, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, ST3GalIA,1, ST3O
Gene
UniProtKB-ID: SIA4A_HUMAN, A0A024R9L6_HUMAN
UniprotKB: Q11201, A0A024R9L6
UniParc: UPI00000015E1
EMBL: AF059321, BC018357, CH471060, L29555, L13972
Ensembl: ENSG00000008513
KO: hsa:6482
Nucleutide sequences
EMBL-CDS: AAC17874.1, AAA36612.1, AAH18357.1, AAC37574.1, EAW92173.1, EAW92174.1, EAW92172.1
Gene_ORFName: hCG_33465
Ensembl_TRS: ENST00000521180, ENST00000522652, ENST00000648219, ENST00000399640
Protein sequencees
Ensembl_PRO: ENSP00000430515, ENSP00000428540, ENSP00000414073, ENSP00000497381
RefSeq: XP_006716680.1, NP_003024.1, XP_016869225.1, XP_005251082.1, XP_024303001.1, XP_011515527.1, NP_775479.1
Others
UniRef100: UniRef100_Q11201
UniRef90: UniRef90_Q11201
UniRef50: UniRef50_Q11201
UniGene: Hs.374257
CCDS: CCDS6373.1

全选

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