| Type | Description |
|---|---|
| Definition | exonuclease 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:15:00 | Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis. | 31616062 |
| 2019-01-26 11:20:00 | Three of them [PLEC (OR = 6.28, p = 6.42 x 10(-23) ) (p.Arg2016Trp), EXO5 (OR = 3.37, p = 4.82 x 10(-09) ) (p.Arg344AlafsTer10) and DNAH7 (OR = 1.64, p = 0.048)] were replicated as potential candidates. | 29761480 |
| 2013-02-16 10:26:00 | The human homolog (C1orf176; EXO5) that functions in the repair of nuclear DNA damage. | 23095756 |
| Type | IDs |
|---|---|
| Synonymous | C1orf176, DEM1, Exo V, hExo5 |
| Gene |
UniProtKB-ID:
EXO5_HUMAN
UniprotKB:
Q9H790
UniParc:
UPI00000722CF
EMBL:
CH471059,
AL603839,
AK024797,
BC021969
Ensembl:
ENSG00000164002
KO:
hsa:64789
|
| Nucleutide sequences |
EMBL-CDS:
EAX07213.1,
EAX07211.1,
EAX07214.1,
BAB15008.1,
EAX07210.1,
AAH21969.1,
EAX07212.1
Ensembl_TRS:
ENST00000358527,
ENST00000372703,
ENST00000296380
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361788,
ENSP00000296380,
ENSP00000351328
RefSeq:
NP_001333879.1,
NP_001333878.1,
NP_001333884.1,
NP_001333877.1,
NP_073611.1,
NP_001333881.1,
NP_001333880.1,
NP_001333882.1,
NP_001333883.1,
NP_001333875.1,
NP_001333876.1,
XP_016857591.1,
NP_001333885.1,
XP_016857588.1
|
| Others |
UniRef100:
UniRef100_Q9H790
UniRef90:
UniRef90_Q9H790
UniRef50:
UniRef50_Q9H790
UniGene:
Hs.59584
CCDS:
CCDS453.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32487729 |
Proc Natl Acad Sci U S A Antonio Rausell , Yufei Luo , Marie Lopez , Yoann Seeleuthner , Franck Rapaport , Antoine Favier , Peter D Stenson , David N Cooper , Etienne Patin , Jean-Laurent Casanova , Lluis Quintana-Murci , Laurent Abel |
2020-06-16 | - |
| 32461654 |
The mutational constraint spectrum quantified from variation in 141,456 humans. Nature Konrad J Karczewski , Laurent C Francioli , Grace Tiao , Beryl B Cummings , Jessica Alföldi , Qingbo Wang , Ryan L Collins , Kristen M Laricchia , Andrea Ganna , Daniel P Birnbaum , Laura D Gauthier , Harrison Brand , Matthew Solomonson , Nicholas A Watts , Daniel Rhodes , Moriel Singer-Berk , Eleina M England , Eleanor G Seaby , Jack A Kosmicki , Raymond K Walters , Katherine Tashman , Yossi Farjoun , Eric Banks , Timothy Poterba , Arcturus Wang , Cotton Seed , Nicola Whiffin , Jessica X Chong , Kaitlin E Samocha , Emma Pierce-Hoffman , Zachary Zappala , Anne H O'Donnell-Luria , Eric Vallabh Minikel , Ben Weisburd , Monkol Lek , James S Ware , Christopher Vittal , Irina M Armean , Louis Bergelson , Kristian Cibulskis , Kristen M Connolly , Miguel Covarrubias , Stacey Donnelly , Steven Ferriera , Stacey Gabriel , Jeff Gentry , Namrata Gupta , Thibault Jeandet , Diane Kaplan , Christopher Llanwarne , Ruchi Munshi , Sam Novod , Nikelle Petrillo , David Roazen , Valentin Ruano-Rubio , Andrea Saltzman , Molly Schleicher , Jose Soto , Kathleen Tibbetts , Charlotte Tolonen , Gordon Wade , Michael E Talkowski , Genome Aggregation Database Consortium , Benjamin M Neale , Mark J Daly , Daniel G MacArthur |
2020-05-01 | - |
| 31616062 |
Oncogene Shafat Ali , Yilan Zhang , Mian Zhou , Hongzhi Li , Weiwei Jin , Li Zheng , Xiaochun Yu , Jeremy M Stark , Jeffrey N Weitzel , Binghui Shen |
2020-02-01 | - |
| 29761480 |
Int J Cancer Beatriz Paumard-Hernández , Oriol Calvete , Lucia Inglada Pérez , Héctor Tejero , Fátima Al-Shahrour , Guillermo Pita , Alicia Barroso , Juan Carlos Triviño , Miguel Urioste , Claudia Valverde , Enrique González Billalabeitia , Vanesa Quiroga , Juan Francisco RodrÃguez Moreno , Antonio Fernández Aramburo , Cristina López , Pablo Maroto , Javier Sastre , MarÃa José Juan Fita , Ignacio Duran , Isabel Lorenzo-Lorenzo , Patricia Iranzo , Xavier GarcÃa Del Muro , Silverio Ros , Francisco Zambrana , Ana MarÃa Autran , Javier BenÃtez |
2018-10-15 | - |
| 25807282 |
Identification of a large set of rare complete human knockouts. Nat. Genet. Patrick Sulem , Hannes Helgason , Asmundur Oddson , Hreinn Stefansson , Sigurjon A Gudjonsson , Florian Zink , Eirikur Hjartarson , Gunnar Th Sigurdsson , Adalbjorg Jonasdottir , Aslaug Jonasdottir , Asgeir Sigurdsson , Olafur Th Magnusson , Augustine Kong , Agnar Helgason , Hilma Holm , Unnur Thorsteinsdottir , Gisli Masson , Daniel F Gudbjartsson , Kari Stefansson |
2015-05-01 | - |
| 23095756 |
Human exonuclease 5 is a novel sliding exonuclease required for genome stability. J Biol Chem Justin L Sparks , Rakesh Kumar , Mayank Singh , Marc S Wold , Tej K Pandita , Peter M Burgers |
2012-12-14 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 17207965 |
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics Philippe Lamesch , Ning Li , Stuart Milstein , Changyu Fan , Tong Hao , Gabor Szabo , Zhenjun Hu , Kavitha Venkatesan , Graeme Bethel , Paul Martin , Jane Rogers , Stephanie Lawlor , Stuart McLaren , Amélie Dricot , Heather Borick , Michael E Cusick , Jean Vandenhaute , Ian Dunham , David E Hill , Marc Vidal |
2007-03-01 |
GNPDA1,
CTAGE4,
BCL2L11,
PIGK,
TIMM23,
NPIPA5,
CST8,
AP1M2,
COX17,
TIMM23B,
SNX29P1,
IL18BP,
RWDD2B,
TSSC4,
UPK1A-AS1,
ARPC5,
ARPC3,
TSPAN5,
TSPAN3,
TSPAN1,
PPIF,
CTDSP2,
NAMPT,
PDZK1IP1,
DHRS9,
RBM7,
MPHOSPH6,
DHRS2,
MPZL2,
GPA33,
CALCOCO2,
SPRY3,
SPRY1,
RAMP3,
TRAIP,
DNAJA2,
IKZF1,
CRISP3,
SIRPB1,
CNPY2,
B3GNT3,
WARS2,
NPM3,
CDO1,
CACNG3,
TUBB4B,
CEPT1,
PEMT,
WFDC2,
NSA2,
EMG1,
TIMM17A,
PPIE,
HAX1,
CIB2,
DCTN2,
RPP38,
SLC35A1,
IFI44,
CXCL13,
SIVA1,
MRPL28,
CENPA,
MAB21L2,
RAD51AP1,
MTX2,
CGRRF1,
DCTN6,
B3GNT2,
CLDN16,
PNMA2,
KLRA1P,
SRSF10,
ARPP21,
STARD10,
CGA,
EDDM3A,
CFHR3,
GPR83,
RAB10,
CPSF4,
RUNDC3A,
COPS8,
C11orf58,
CCDC85B,
GLIPR1,
KLK11,
SNRNP27,
LIAS,
LILRA2,
SNRNP35,
CYB561D2,
ESM1,
WDR5,
BTN2A1,
HHLA3,
BVES,
KLK8,
MRPL3
|
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 15342556 |
Genome Res. Yutaka Suzuki , Riu Yamashita , Matsuyuki Shirota , Yuta Sakakibara , Joe Chiba , Junko Mizushima-Sugano , Kenta Nakai , Sumio Sugano |
2004-09-01 |
GNE,
HCN4,
GPR75-ASB3,
LOC100507431,
ZHX1-C8orf76,
NR1H3,
SERF2,
LOC101929134,
RNF41,
CDK5,
NUTF2,
RCAN2,
GLYAT,
RAMP3,
SMIM11B,
CT45A8,
NET1,
NMUR1,
TNIP1,
SIRPB1,
EMC8,
BTN2A2,
DLC1,
ATP8A1,
TUBGCP3,
EMG1,
TOMM40,
CEACAM5,
SEC23B,
UNC13B,
APPBP2,
FBLN5,
DDX17,
HYOU1,
ATG7,
BATF,
GLRX3,
HTATIP2,
RPP38,
PDLIM5,
ERLIN1,
TGOLN2,
POLR3G,
POSTN,
IGF2BP1,
DMRT2,
CELF2,
CCT6B,
CCT8,
POLQ,
NUDC,
PTGES3,
PLK4,
POP4,
NEK6,
GJB6,
UTP14A,
FRS2,
USP20,
CD300C,
WDR3,
DHRS4,
BLCAP,
SUGT1,
POP1,
C11orf58,
TMED2,
SLC38A3,
IL24,
ATF7,
RAB35,
LILRA2,
UBE2C,
CYB561D2,
RPP14,
CHEK1,
HIBADH,
FOXN3,
RCAN3,
SLC7A9,
HHLA2,
ERLIN2,
FAM107A,
CHIT1,
IRAK3,
AKAP10,
DUSP10,
CA5B,
SAT2,
FILIP1L,
GLMP,
WDR89,
PARK7,
ADCY7,
VSIG4,
MGLL,
SMIM12,
SYNPO,
HENMT1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员