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64786 TBC1D15

64786

TBC1D15

TBC1 domain family member 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition TBC1 domain family member 15

研究结论

Date Results Publications
2020-08-29 12:49:00 p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs. 32555153
2020-07-11 12:37:00 Here, we demonstrate that this cellular cholesterol imbalance is due to AnxA6 promoting Rab7 inactivation via TBC1D15, a Rab7-GAP. 31664461
2018-11-10 12:01:00 Report provides evidence for a new function of TBC1D15 in the control of GLUT4 vesicles translocation through regulating Rab7 activity. Glucose uptake was greatly reduced when TBC1D15 was knocked out. 30316925
2015-11-28 11:24:00 Demonstrate that TBC1D15 and TBC1D17 mediate proper autophagic encapsulation of mitochondria by regulating Rab7 activity at the interface between mitochondria and isolation membranes. 24569479
2014-11-08 12:09:00 TBC1D15 is required for the accumulation of RhoA. 24337944

名称对应

Type IDs
Synonymous RAB7-GAP
Gene
UniProtKB-ID: TBC15_HUMAN, A8K8E1_HUMAN
UniprotKB: Q8TC07, A8K8E1
UniParc: UPI0000E59825, UPI00001FC7A7, UPI000199130B, UPI000049DD7C
EMBL: AB449901, AK022147, BC028352, CH471054, AC089984, AC090109, AK292306, AK297626
Ensembl: ENSG00000121749
KO: hsa:64786
Nucleutide sequences
EMBL-CDS: BAG60001.1, BAH16644.1, AAH28352.1, BAB13971.1, EAW97276.1, BAF84995.1
Gene_ORFName: hCG_25175
Ensembl_TRS: ENST00000485960, ENST00000550746, ENST00000319106
Protein sequencees
Ensembl_PRO: ENSP00000420678, ENSP00000448182, ENSP00000318262
RefSeq: XP_006719628.1, NP_001372783.1, NP_001139685.2, XP_006719627.1, XP_011536983.1, XP_011536981.1, NP_001372779.1, NP_001372778.1, XP_016875316.1, XP_011536982.1, NP_001372781.1, NP_001372777.1, NP_001372782.1, NP_001139686.2, NP_001372780.1, XP_011536984.1, NP_073608.4
Others
UniRef100: UniRef100_A8K8E1, UniRef100_Q8TC07
UniRef90: UniRef90_Q8TC07
UniRef50: UniRef50_Q8TC07
UniGene: Hs.284630
CCDS: CCDS31858.1, CCDS53814.1

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