| Type | Description |
|---|---|
| Definition | RNA binding motif protein 15 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:28:00 | Study has shown that MED12 mutations can be heterogeneous in both synchronous and recurrent phyllodes tumor unlike TERT mutations. Authors have also shown that RBM15 mutations may be important in the pathogenesis of borderline/malignant phyllodes tumors. | 29315289 |
| 2016-10-29 12:03:00 | The authors demonstrate that RBM15 is methylated by protein arginine methyltransferase 1 (PRMT1) at residue R578, leading to its degradation via ubiquitylation by an E3 ligase (CNOT4). | 26575292 |
| 2015-04-25 10:21:00 | OTT1 regulates the alternative splicing of Mpl-TR, a truncated isoform of c-Mpl, which modulates Thrombopoietin-mediated signaling. | 25468569 |
| 2013-06-22 10:40:00 | RBM15 does indeed play a critical role in the survival of chronic myelogenous leukemia (CML) cells, which may have potential application in designing molecular therapies for CML treatment. | 22497198 |
| 2013-02-02 11:25:00 | both Rbm15 and the leukemogenic Rbm15-Mkl1 fusion protein interact with the Setd1b histone H3-Lys4 methyltransferase | 22927943 |
| Type | IDs |
|---|---|
| Synonymous | OTT, OTT1, SPEN |
| Gene |
UniProtKB-ID:
RBM15_HUMAN
UniprotKB:
Q96T37
UniParc:
UPI0000070B17,
UPI000006DAFA,
UPI000013E1C5,
UPI000020527E
EMBL:
AL355488,
BC047479,
BC103507,
AF368064,
AK025596,
CH471122,
BC098140,
AF368063,
BC006397,
AJ303089,
AJ297259,
BC062316,
BC103493,
AJ303090,
AK022541,
BK005915,
AF368062,
AF364035
Ensembl:
ENSG00000162775
KO:
hsa:64783
|
| Nucleutide sequences |
EMBL-CDS:
CAC38829.1,
AAH98140.1,
BAB14088.1,
AAI03494.1,
AAI03508.1,
CAC38828.1,
CAC38862.1,
AAH62316.1,
DAA05818.1,
AAK54722.1,
EAW56439.1,
AAK54723.1,
AAH06397.2,
AAK56920.1,
AAK54724.1,
AAH47479.1,
CAC38861.1,
BAB15185.1
Ensembl_TRS:
ENST00000652342,
ENST00000369784,
ENST00000618772,
ENST00000487146,
ENST00000602849,
ENST00000652747
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498634,
ENSP00000483133,
ENSP00000498328,
ENSP00000473638,
ENSP00000473552,
ENSP00000358799
RefSeq:
NP_001188474.1,
NP_073605.4
|
| Others |
UniRef100:
UniRef100_Q96T37
UniRef90:
UniRef90_Q96T37
UniRef50:
UniRef50_Q96T37
UniGene:
Hs.435947,
Hs.708172
CCDS:
CCDS822.1,
CCDS59198.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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