| Type | Description |
|---|---|
| Definition | siah E3 ubiquitin protein ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:30:00 | TRAF4, a new substrate of SIAH1, participates in chemotherapy resistance of breast cancer cell by counteracting SIAH1-mediated downregulation of beta-catenin. | 32671611 |
| 2020-09-19 16:27:00 | Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2. | 32479599 |
| 2020-06-27 12:49:00 | Depletion of Siah1 enhanced Akt3 levels in the soma and axonal tips, eliciting multiple branching. | 31471318 |
| 2019-12-14 12:17:00 | PHF19 promotes the proliferation, migration, and chemosensitivity of glioblastoma to doxorubicin through modulation of the SIAH1/beta-catenin axis. | 30323224 |
| 2019-03-23 11:34:00 | Data suggest that lncRNA small nucleolar RNA host gene 1, as a pathogenic factor, promotes alpha-synuclein aggregation and toxicity by targeting the miR-15b-5p/seven in absentia homolog 1 axis. | 29217406 |
| Type | IDs |
|---|---|
| Synonymous | SIAH1A |
| Gene |
UniProtKB-ID:
SIAH1_HUMAN
UniprotKB:
Q8IUQ4
UniParc:
UPI0000073CF6,
UPI0000E5E33B,
UPI0000074729
EMBL:
BC044920,
EF026094,
BX647064,
BC035562,
BC042550,
AJ400626,
U63295,
U76247
Ensembl:
ENSG00000196470
KO:
hsa:6477
|
| Nucleutide sequences |
EMBL-CDS:
CAE46191.1,
AAH42550.1,
AAC12950.1,
ABK15529.1,
AAH44920.1,
AAC51907.1,
CAC35542.1,
AAH35562.1
Ensembl_TRS:
ENST00000568007,
ENST00000394725,
ENST00000356721,
ENST00000380006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369343,
ENSP00000349156,
ENSP00000456421,
ENSP00000378214
RefSeq:
NP_001006611.1,
XP_024306162.1,
XP_011521581.1,
XP_006721309.1,
NP_003022.3,
XP_024306163.1
|
| Others |
UniRef100:
UniRef100_Q8IUQ4
UniRef90:
UniRef90_Q8IUQ4
UniRef50:
UniRef50_Q8IUQ4
UniGene:
Hs.706828
CCDS:
CCDS32444.1,
CCDS10735.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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