| Type | Description |
|---|---|
| Definition | SMAD specific E3 ubiquitin protein ligase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:49:00 | Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled. | 32392721 |
| 2021-02-02 13:26:00 | Ubiquitin ligase SMURF2 enhances epidermal growth factor receptor stability and tyrosine-kinase inhibitor resistance. | 32669362 |
| 2020-12-05 12:59:00 | Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis. | 32361710 |
| 2020-11-28 13:11:00 | SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis. | 32103168 |
| 2020-10-03 12:54:00 | TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2. | 31076633 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SMUF2_HUMAN,
Q96DE7_HUMAN
UniprotKB:
Q9HAU4,
Q96DE7
UniParc:
UPI000006DD5A,
UPI00001361C5
EMBL:
BC009527,
AF310676,
AF301463,
BC111945,
AY014180,
BC093876
Ensembl:
ENSG00000108854
KO:
hsa:64750
|
| Nucleutide sequences |
EMBL-CDS:
AAG25641.1,
AAG50421.1,
AAH93876.1,
AAG45422.1,
AAI11946.1,
AAH09527.1
Ensembl_TRS:
ENST00000262435
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262435
RefSeq:
XP_005257642.1,
NP_073576.1
|
| Others |
UniRef100:
UniRef100_Q9HAU4
UniRef90:
UniRef90_Q9HAU4
UniRef50:
UniRef50_Q9HAU4
UniGene:
Hs.515011
CCDS:
CCDS32707.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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