| Type | Description |
|---|---|
| Definition | HtrA serine peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | HtrA2 is required for inflammatory responses in BMDMs via controlling TRAF2 stability in collagen-induced arthritis. | 33229071 |
| 2020-10-03 12:56:00 | Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart. | 31627188 |
| 2020-08-01 11:43:00 | This study showed that ALDH2 deficiency upregulated the mitochondrial serine protease Omi/HtrA2, and that ALDH2 deficiency leads to greater mitochondrial production, but homeostasis can be maintained via an appropriate stress response. | 32048867 |
| 2020-06-27 12:19:00 | Findings indicate the expression of both HtrA serine peptidase 2 (Omi/HtrA2) and tumor supressor p53 (p53) nucleoprotein were elevated in aging heart. | 31543347 |
| 2020-06-20 11:20:00 | Suppressing HtrA2/Omi expression promotes hepatic fibrogenesis via modulating mitochondrial reactive oxygen species generation; these novel mechanistic insights involving the regulation of mitochondrial homeostasis by HtrA2/Omi may be of importance for developing new therapeutic strategies for hepatic fibrosis. | 31547195 |
| Type | IDs |
|---|---|
| Synonymous | AI481710, Omi, Prss25, mnd2 |
| Gene |
UniProtKB-ID:
HTRA2_MOUSE
UniprotKB:
Q9JIY5
UniParc:
UPI0000028679
EMBL:
AF164513,
AF175324
Ensembl:
ENSMUSG00000068329
KO:
mmu:64704
|
| Nucleutide sequences |
EMBL-CDS:
AAF89534.1,
AAD50499.1
Ensembl_TRS:
ENSMUST00000089645
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087073
RefSeq:
NP_062726.3
|
| Others |
UniRef100:
UniRef100_Q9JIY5
UniRef90:
UniRef90_Q9JIY5
UniRef50:
UniRef50_O43464-3
UniGene:
Mm.21880
CCDS:
CCDS20267.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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