| Type | Description |
|---|---|
| Definition | nischarin |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:07:00 | These data suggest that IRAS/Nischarin may play an important role in the development of morphine tolerance and physical dependence in vivo through modulating MOR expression, as well as AMPA GluR1-S845 phosphorylation, which might be one of the mechanisms underlying the development of opiate addiction. | 30902386 |
| 2017-10-21 11:52:00 | results indicate that Nisch is an important AMPK inhibitor and a critical regulator of energy homeostasis, including lipid and glucose metabolism. | 28842496 |
| 2017-09-16 12:06:00 | We identified a significant genetic interaction between Nisch and Itga5; mice heterozygous for Itga5-null and homozygous for edison mutations display a significantly increased penetrance and severity of chronic otitis media. | 28806779 |
| 2016-07-02 11:45:00 | Nischarin inhibits neurite outgrowth by blocking PAK1 activation in neurons. | 26670864 |
| 2014-03-15 11:30:00 | Data from studies using various receptor antagonists/agonists suggest that imidazoline receptors (Nisch I-1), alpha2-adrenoceptors, and endothelin-A receptors are involved in body temperature regulation in mice. | 22681550 |
| Type | IDs |
|---|---|
| Synonymous | 1200007D05Rik, 3202002H23Rik, AW494485, I-1, edsn |
| Gene |
UniProtKB-ID:
NISCH_MOUSE,
Q8CF63_MOUSE
UniprotKB:
Q80TM9,
Q8CF63
UniParc:
UPI00017BE79D,
UPI00001E8BD1,
UPI00000E9034,
UPI00000E94D9,
UPI000024E095,
UPI00000E9D38,
UPI0000021D58,
UPI00000E9F84
EMBL:
BC003270,
BC108364,
AK122412,
AF315344,
AC154446,
AC108416,
AK004628,
AK086880,
AY032852,
AK036043,
AF144133,
AK080441
Ensembl:
ENSMUSG00000021910
KO:
mmu:64652
|
| Nucleutide sequences |
EMBL-CDS:
AAD31521.1,
AAI08365.1,
BAC39757.1,
BAC29286.1,
AAG42100.1,
AAH03270.1,
BAC37917.1,
AAK52087.1,
BAC65694.1,
BAC25092.1
Ensembl_TRS:
ENSMUST00000171735,
ENSMUST00000165981,
ENSMUST00000022469,
ENSMUST00000168206,
ENSMUST00000164989,
ENSMUST00000172142
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132842,
ENSMUSP00000126982,
ENSMUSP00000022469,
ENSMUSP00000132413,
ENSMUSP00000127132,
ENSMUSP00000130210
RefSeq:
NP_073147.2,
XP_017171604.1,
XP_036014672.1,
XP_017171605.1,
NP_001334512.1
|
| Others |
UniRef100:
UniRef100_Q8CF63,
UniRef100_Q80TM9
UniRef90:
UniRef90_Q80TM9,
UniRef90_Q8CF63
UniRef50:
UniRef50_Q9Y2I1,
UniRef50_Q8CF63
UniGene:
Mm.298728
CCDS:
CCDS84107.1,
CCDS36853.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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