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64633 Rab5a

64633

Rab5a

RAB5A, member RAS oncogene family

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition RAB5A, member RAS oncogene family

研究结论

Date Results Publications
2020-10-24 13:56:00 c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling. 30988348
2018-01-27 10:46:00 Retrieval is also dependent on the Rab5 effector Fused Toes (FTS)-Hook-FTS and Hook-interacting protein (FHIP) (FHF) complex, which interacts with the minus-end-directed microtubule motor dynein and its activator dynactin to drive a population of axonal retrograde carriers containing somatodendritic proteins toward the soma. 27559088
2015-05-16 10:05:00 Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections. 25161316
2013-09-14 10:36:00 In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. 23687301
2012-06-16 10:41:00 The reduction of vesicles exhibiting directional mobility induced by Rab5 mutants indicates that GTP-GDP switching is required for maintaining directional mobility. 22279005

名称对应

Type IDs
Gene
UniProtKB-ID: RAB5A_RAT
UniprotKB: M0RC99
UniParc: UPI000019B86D
EMBL: AABR06079878, AF072935, BC161848, CH474184
KO: rno:64633, rno:100361891
Nucleutide sequences
EMBL-CDS: AAC26004.1, EDL82849.1, AAI61848.1
Protein sequencees
RefSeq: NP_073183.1
Others
UniRef100: UniRef100_M0RC99
UniRef90: UniRef90_P20339
UniRef50: UniRef50_P20339
UniGene: Rn.44477

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