| Type | Description |
|---|---|
| Definition | basonuclin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:28:00 | Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. | 31065688 |
| 2020-07-11 10:41:00 | Cell heterogeneity is conserved in human epicardium, regulated by BNC1 and associated with cell fate and function. | 31767620 |
| 2019-04-27 12:12:00 | A female mouse model of the human Bnc1 frameshift mutation exhibited infertility, significantly increased serum follicle-stimulating hormone, decreased ovary size and reduced follicle numbers, consistent with primary ovarian insufficiency (POI). Haploinsufficiency of BNC1 as an etiology of human autosomal dominant POI was reported. | 30010909 |
| 2016-10-22 11:02:00 | Study shows that BNC1 expression was down-regulated in hepatocellular tumors and cell lines through its promotor hypermethylation. | 26821013 |
| 2015-04-25 10:19:00 | Study demonstrates that Bnc1 regulates epithelial plasticity of mammary epithelial cells and influences outcome of TGF-beta1 signaling. | 24662832 |
| Type | IDs |
|---|---|
| Synonymous | BNC, BSN1, HsT19447 |
| Gene |
UniProtKB-ID:
BNC1_HUMAN,
F5GY04_HUMAN,
B7Z885_HUMAN
UniprotKB:
Q01954,
F5GY04,
B7Z885
UniParc:
UPI000206522C,
UPI0000126796,
UPI00019151F3
EMBL:
U59693,
U59692,
L03427,
U59694,
AK302992,
AC103876
Ensembl:
ENSG00000169594
KO:
hsa:646
|
| Nucleutide sequences |
EMBL-CDS:
AAA35584.1,
AAB53028.1,
BAH13871.1
Ensembl_TRS:
ENST00000345382,
ENST00000569704
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307041,
ENSP00000456727
RefSeq:
XP_011520195.1,
NP_001708.3,
XP_011520196.1,
NP_001288135.1
|
| Others |
UniRef100:
UniRef100_B7Z885,
UniRef100_F5GY04,
UniRef100_Q01954
UniRef90:
UniRef90_Q01954
UniRef50:
UniRef50_Q01954
UniGene:
Hs.459153
CCDS:
CCDS10324.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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