| Type | Description |
|---|---|
| Definition | SH3 domain containing GRB2 like 1, endophilin A2 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 11:02:00 | EV71 enters Caco-2 cells mainly via an endophilin-A2-mediated endocytic pathway. | 31132962 |
| 2019-05-11 12:58:00 | FBP17 and CIP4 prime the membrane of resting cells for fast endophilin-mediated endocytosis by recruiting the 5'-lipid phosphatase SHIP2 and lamellipodin to mediate the local production of phosphatidylinositol-3,4-bisphosphate and endophilin pre-enrichment. | 30061681 |
| 2018-07-14 12:14:00 | Study observed elevated EA2 gene expression in the subcutaneous compared to that in the visceral human adipose tissue. EA2 gene expression negatively correlated with adiponectin and chemerin in visceral adipose tissue, and positively correlated with TNF-alpha in subcutaneous adipose tissue. EA2 gene expression was significantly downregulated during differentiation of preadipocytes in vitro. | 29113429 |
| 2018-06-09 10:55:00 | Our study provides novel evidence of Endo II function in HER2+ cancer cell motility and trafficking of HER2 that relates to effective treatments with trastuzumab or T-DM1. Thus, differential expression of Endo II may relate to sensitivity or resistance to trastuzumab-based therapies for HER2+ cancers | 28974266 |
| 2018-03-03 11:32:00 | Expression level of SH3GL1 was widely upregulated in human OS tissues, and their overexpression was significantly correlated with more aggressive clinicopathological features. | 28702842 |
| Type | IDs |
|---|---|
| Synonymous | CNSA1, EEN, SH3D2B, SH3P8 |
| Gene |
UniProtKB-ID:
SH3G1_HUMAN,
Q6FGM0_HUMAN
UniprotKB:
Q99961,
Q6FGM0
UniParc:
UPI00003E605D,
UPI0001AE63BD,
UPI0000135931
EMBL:
AK299166,
CH471139,
AC007292,
CR542087,
AK315450,
U65999,
AC011498,
AK097616,
AY364240,
BC098565,
BC001270,
X99656,
AF190465
Ensembl:
ENSG00000141985
KO:
hsa:6455
|
| Nucleutide sequences |
EMBL-CDS:
AAF04290.1,
AAH01270.1,
BAG61213.1,
AAB86800.1,
CAA67970.1,
CAG46884.1,
AAQ76799.1,
BAG37838.1,
EAW69228.1,
EAW69229.1,
AAH98565.1
Gene_ORFName:
hCG_21932
Ensembl_TRS:
ENST00000417295,
ENST00000269886,
ENST00000598564
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000470792,
ENSP00000404568,
ENSP00000269886
RefSeq:
NP_001186872.1,
XP_016882635.1,
XP_011526485.1,
NP_001186873.1,
NP_003016.1
|
| Others |
UniRef100:
UniRef100_Q99961
UniRef90:
UniRef90_Q99961
UniRef50:
UniRef50_Q99961
UniGene:
Hs.97616
CCDS:
CCDS32874.1,
CCDS59335.1,
CCDS56076.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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