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64537 Hpse

64537

Hpse

heparanase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition heparanase

研究结论

Date Results Publications
2019-09-28 11:04:00 We identified Hpse as a previously unexplored candidate, being up-regulated following injury. We confirmed these results and demonstrated inhibition of Hpse led to an acceleration of axonal degeneration, accompanied by an increase in b-catenin 29581478
2018-04-14 10:39:00 Heparanase plays an important role in mediating the neuroinflammatory response after subarachnoid hemorrhage. 28720149
2017-10-14 12:20:00 Endothelial cell-to-cardiomyocyte transfer of heparanase to modulates the cardiomyocyte cell death signature. This mechanism was observed in the acutely diabetic heart, and its interruption following chronic diabetes may contribute towards the development of diabetic cardiomyopathy. 27979811
2016-12-31 10:48:00 the expression of the gene for heparanase was increased in the right and left ventricles after treatment with monocrotaline 26638897
2014-10-11 12:51:00 Inhibiting heparanase function could offer a new strategy for managing cardiomyopathy observed after diabetes. 24608441

名称对应

Type IDs
Synonymous Hep, Hpa
Gene
UniProtKB-ID: HPSE_RAT
UniprotKB: Q71RP1
UniParc: UPI000021FCE8
EMBL: AF184967, AF359508
KO: rno:64537
Nucleutide sequences
EMBL-CDS: AAQ15189.1, AAF04563.1
Protein sequencees
RefSeq: NP_072127.1
Others
UniRef100: UniRef100_Q71RP1
UniRef90: UniRef90_Q6YGZ1
UniRef50: UniRef50_Q9Y251-2
UniGene: Rn.6392

全选

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研究热度

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