| Type | Description |
|---|---|
| Definition | thimet oligopeptidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-06-28 10:46:00 | Coincubation of Kiss1 and EP24.15 demonstrated multiple cleavages of the peptide in vitro. immunohistochemistry indicated coexpression of EP24.15 and Kiss1, implicating that the regulation of Kiss1 by EP24.15 could occur in vivo. | 26653570 |
| 2013-12-21 10:35:00 | we show that Ang-(1-7) is the main metabolite of angiotensin I in rat hippocampi, and, strikingly, that thimet oligopeptidase is the main enzyme involved in the generation of Ang-(1-7). | 24041943 |
| 2012-05-12 10:04:00 | TOP changes in the brain could play important role in the balance of neuropeptide level correlated with cocaine effects. | 22387539 |
| 2010-01-21 00:00:00 | this is the first evidence of an in vivo role for EP 24.15 in brain function, specifically in regulating alterations in microvessel permeability induced by exogenous bradykinin | 12586639 |
| 2010-01-21 00:00:00 | increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load | 18571100 |
| Type | IDs |
|---|---|
| Synonymous | EP24.15 |
| Gene |
UniProtKB-ID:
THOP1_RAT
UniprotKB:
P24155
UniParc:
UPI000042AE53
EMBL:
M61142,
BC081706
Ensembl:
ENSRNOG00000019924
KO:
rno:64517
|
| Nucleutide sequences |
EMBL-CDS:
AAH81706.1,
AAA41586.1
Ensembl_TRS:
ENSRNOT00000027045
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000027045
RefSeq:
XP_006241057.1,
NP_742072.2
|
| Others |
UniRef100:
UniRef100_P24155
UniRef90:
UniRef90_P24155
UniRef50:
UniRef50_P24155
UniGene:
Rn.9490
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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