| Type | Description |
|---|---|
| Definition | tryptase beta 2 (gene/pseudogene) |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:36:00 | Allosteric effects of alpha-tryptase protomers on neighboring beta-tryptase protomers likely result in the novel substrate repertoire of alpha/beta-tryptase tetramers that in turn cause some of the clinical features of hereditary alpha-tryptasemia and of other disorders involving mast cells. | 31337736 |
| 2014-02-22 10:09:00 | These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. | 24142694 |
| 2010-01-21 00:00:00 | The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. | 17449330 |
| 2010-01-21 00:00:00 | Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. | 15567416 |
| 2010-01-21 00:00:00 | Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. | 19748655 |
| Type | IDs |
|---|---|
| Synonymous | TPS2, tryptaseB, tryptaseC |
| Gene |
UniProtKB-ID:
TRYB2_HUMAN,
A0A140VJT7_HUMAN
UniprotKB:
P20231,
A0A140VJT7
UniParc:
UPI0000169899,
UPI0000137302
EMBL:
AF099143,
FJ931117,
AF099145,
BC029356,
FJ931120,
M33492,
M37488,
AC120498,
HM005476,
M33493,
AF099146,
S55551
Ensembl:
ENSG00000197253
KO:
hsa:64499,
hsa:7177
|
| Nucleutide sequences |
EMBL-CDS:
AAD17859.2,
AAA51843.1,
AAD17858.1,
AAA36780.1,
AAH29356.1,
AAA36779.1,
AAD13876.1,
ACZ98913.1,
AAD17857.1,
ACZ98911.1,
AEE61074.1
Ensembl_TRS:
ENST00000606293
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482743
RefSeq:
NP_077078.5
|
| Others |
UniRef100:
UniRef100_A0A087X1U0,
UniRef100_Q15661
UniRef90:
UniRef90_Q15661
UniRef50:
UniRef50_Q15661
UniGene:
Hs.405479,
Hs.592982
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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