| Type | Description |
|---|---|
| Definition | small glutamine rich tetratricopeptide repeat containing alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 12:35:00 | The SGTA is a co-chaperone that, in collaboration with the complex of BAG6, facilitates the biogenesis and quality control of hydrophobic proteins, protecting them from the aqueous cytosolic environment. | 30635083 |
| 2019-05-18 10:12:00 | the results provide novel insights into the structural complexity of SGTA and provide a new basis for mechanistic studies of substrate binding and release at the C-terminal region. | 29996828 |
| 2018-05-12 11:20:00 | evidence that the interaction can mediate the association of Rpn13 and SGTA in a cellular context. | 27827410 |
| 2018-01-20 10:42:00 | Coimmunoprecipitation studies indicated that non-glycosylated tetherin is stabilized through the formation of a ternary SGTA/Vpu/tetherin complex. Although the results do not provide support for a physiological function of SGTA in HIV-1 replication, they demonstrate that SGTA overexpression regulates tetherin expression and stability, thus providing insights into the function of SGTA in endoplasmic reticulum translocation | 27103333 |
| 2017-07-29 12:53:00 | study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA controls Hsc70 to impact this process | 28356524 |
| Type | IDs |
|---|---|
| Synonymous | SGT, alphaSGT, hSGT |
| Gene |
UniProtKB-ID:
SGTA_HUMAN
UniprotKB:
O43765
UniParc:
UPI000013592E
EMBL:
CH471139,
AJ133129,
BC008885,
BC002989,
BC000390,
AJ223828,
CR542282,
AF408399,
AF368279,
BC005165,
AL050156,
AC006538,
CR533517
Ensembl:
ENSG00000104969
KO:
hsa:6449
|
| Nucleutide sequences |
EMBL-CDS:
CAB43297.2,
AAH08885.1,
AAH00390.1,
AAD13117.1,
CAA11565.1,
AAH02989.2,
EAW69366.1,
EAW69368.1,
CAG47077.1,
CAG38548.1,
AAH05165.1,
AAP29457.1,
AAL01051.1,
EAW69367.1,
CAB39725.1
Ensembl_TRS:
ENST00000221566
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000221566
RefSeq:
XP_011526480.1,
NP_003012.1
|
| Others |
UniRef100:
UniRef100_O43765
UniRef90:
UniRef90_O43765
UniRef50:
UniRef50_O43765
UniGene:
Hs.203910
CCDS:
CCDS12094.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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