| Type | Description |
|---|---|
| Definition | trans-acting transcription factor 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:26:00 | Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. | 31911949 |
| 2017-11-04 12:09:00 | Functional studies revealed that knockdown of Nanog eliminated the mESC self-renewal-promoting ability of Sp5. Finally, we demonstrated that the self-renewal-promoting function of Sp5 was largely dependent on its zinc finger domains | 28961274 |
| 2016-12-17 11:26:00 | Sp5 is able to convert mouse epiblast stem cells into a naive pluripotent state. | 26598557 |
| 2016-09-03 10:52:00 | Sp5/8 bind directly to GC boxes in Wnt target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1/lymphoid enhancer factor (Lef) 1 to facilitate recruitment of beta-catenin to target gene enhancers. | 26969725 |
| 2015-02-21 11:41:00 | Sp5 and Sp8 are pivotal downstream effectors of Wnt3a/beta-catenin that are essential for the self-renewal and differentiation of neuromesodermal stem cells. | 24475213 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SP5_MOUSE
UniprotKB:
Q9JHX2
UniParc:
UPI00000283BA
EMBL:
BC117505,
BC116691,
AK036234,
AF279479
Ensembl:
ENSMUSG00000075304
KO:
mmu:64406
|
| Nucleutide sequences |
EMBL-CDS:
AAI16692.1,
AAI17506.1,
AAF87798.1,
BAC29355.1
Ensembl_TRS:
ENSMUST00000100043
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097620
RefSeq:
NP_071880.1
|
| Others |
UniRef100:
UniRef100_Q9JHX2
UniRef90:
UniRef90_Q9JHX2
UniRef50:
UniRef50_Q9JHX2
UniGene:
Mm.423397
CCDS:
CCDS16106.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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