| Type | Description |
|---|---|
| Definition | G-protein coupled receptor 88 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:31:00 | Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia. | 31666199 |
| 2020-03-07 11:30:00 | Study suggests that GPR88 in dopamine d2 receptor medium spiny neurons shapes defensive and social behavior and contributes in maintaining the inhibition of basal ganglia outputs to control locomotion, stereotypies and motor coordination, while GPR88 in D1R-MSNs promotes novelty habituation and motor learning. | 31346000 |
| 2019-10-12 11:57:00 | Gpr88 deletion disrupts executive, reward, and emotional networks in a configuration that reduces alcohol reward and promotes alcohol seeking and drinking. The functional connectivity signature is reminiscent of alterations observed in individuals at risk for Alcohol use disorder. | 29580570 |
| 2019-04-20 12:25:00 | G-protein coupled receptor 88 knockout (Gpr88 (-/-)) mice showed significantly reduced adiposity accompanied with suppressed spontaneous food intake, particularly pronounced under high fat diet (HFD) treatment. | 28855710 |
| 2019-03-02 12:19:00 | The data of this study suggested that primary sensory perception (olfaction and vision) is intact, but the loss of Gpr88 contributes to delayed behavioral responses that require sensory processing. | 29110094 |
| Type | IDs |
|---|---|
| Synonymous | AW061286, Strg |
| Gene |
UniProtKB-ID:
GPR88_MOUSE,
B2RXU4_MOUSE
UniprotKB:
Q9EPB7,
B2RXU4
UniParc:
UPI0000027290
EMBL:
AB042408,
BC051941,
BC157981,
AB042409
Ensembl:
ENSMUSG00000068696
KO:
mmu:64378
|
| Nucleutide sequences |
EMBL-CDS:
BAB18245.1,
BAB18246.1,
AAH51941.1,
AAI57982.1
Ensembl_TRS:
ENSMUST00000090473
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087959
RefSeq:
XP_006501920.1,
XP_006501919.1,
NP_071872.1
|
| Others |
UniRef100:
UniRef100_Q9EPB7
UniRef90:
UniRef90_Q9EPB7
UniRef50:
UniRef50_Q9EPB7
UniGene:
Mm.40025
CCDS:
CCDS38610.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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