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64362 Des

64362

Des

desmin

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition desmin

研究结论

Date Results Publications
2020-02-08 11:35:00 Desmin participates in the mechanoelectric feedback in heart failure through the NF-kappaB pathway. 31794771
2019-11-09 12:01:00 Aberrant mitochondrial fission results in mitochondrial respiratory defects and apoptotic cell death in D7-Des Tg hearts. Inhibition of aberrant mitochondrial fission using mitochondrial division inhibitor significantly preserved mitochondrial function and decreased apoptotic cell death 29987122
2019-09-21 10:45:00 Ser31 phosphorylated desmin aggregates extensively in cultured cardiomyocytes. Ser31 phosphorylated desmin is a likely candidate seed for the nucleation process leading to cardiac preamyloid oligomer deposition. 29483093
2017-08-19 11:22:00 This study provides new evidence of early onset (24 h) and continuous (4-12 wk) desmin misarrangement and disruption of the normal sarcomeric and mitochondrial architecture throughout the progression of volume overload heart failure, suggesting a causal link between desmin cleavage and mitochondrial disorganization and damage. 28455287
2013-10-26 12:37:00 Data indicte that desmin and h1-calponin are expressed in mesenchymal stem cells (MSC). 23557080

名称对应

Type IDs
Gene
UniProtKB-ID: DESM_RAT
UniprotKB: P48675
UniParc: UPI0000167978
EMBL: X73524
KO: rno:64362
Nucleutide sequences
EMBL-CDS: CAA51920.1
Protein sequencees
RefSeq: NP_071976.2
Others
UniRef100: UniRef100_P48675
UniRef90: UniRef90_P31001
UniRef50: UniRef50_P08670
UniGene: Rn.39196

全选

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研究热度

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