| Type | Description |
|---|---|
| Definition | HCLS1 binding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 11:50:00 | HS1BP3 is localized to ATG16L1- and ATG9-positive autophagosome precursors and we show that HS1BP3 binds phosphatidic acid (PA) through its PX domain. Furthermore, we find the total PA content of cells to be significantly upregulated in the absence of HS1BP3. | 28004827 |
| 2011-10-22 10:15:00 | Results suggest that HS1BP3 regulates apoptosis via HS1 and stimulates AP-1-mediated transcription. | 21699750 |
| 2010-01-21 00:00:00 | Results do not support a role for these DRD3 and HS1BP3 variants in PD. | 19524641 |
| 2010-01-21 00:00:00 | HS1PB3 protein is mutated in essential tremor combined with Parkinson disease. | 16116142 |
| 2010-01-21 00:00:00 | The 828C-->G mutation causes a substitution of a glycine for an alanine residue in the HS1-BP3 protein. It was found in 2 unrelated patients with familial essential tremor. | 15699368 |
| Type | IDs |
|---|---|
| Synonymous | ETM2, HS1-BP3 |
| Gene |
UniProtKB-ID:
H1BP3_HUMAN,
Q9H7U7_HUMAN
UniprotKB:
Q53T59,
Q9H7U7
UniParc:
UPI000013E92A,
UPI000007084B
EMBL:
BC050636,
AC012065,
AK314383,
AK024311,
CH471053
Ensembl:
ENSG00000118960
KO:
hsa:64342
|
| Nucleutide sequences |
EMBL-CDS:
EAX00814.1,
AAH50636.1,
EAX00816.1,
BAG37009.1,
AAX93235.1,
BAB14878.1
Ensembl_TRS:
ENST00000304031
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000305193
RefSeq:
XP_016860187.1,
XP_016860190.1,
XP_016860188.1,
XP_016860189.1,
NP_071905.3,
XP_016860186.1,
XP_016860185.1
|
| Others |
UniRef100:
UniRef100_Q53T59,
UniRef100_Q9H7U7
UniRef90:
UniRef90_Q9H7U7,
UniRef90_Q53T59
UniRef50:
UniRef50_A0A670ITG6,
UniRef50_Q53T59
UniGene:
Hs.531785
CCDS:
CCDS1700.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33001583 |
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A. Thorac Cancer Chun-Guo Mao , Sha-Sha Jiang , Cheng Shen , Tan Long , Hua Jin , Qun-You Tan , Bo Deng |
2020-11-01 | - |
| 32814053 |
Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker |
2020-08-18 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28004827 |
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun Petter Holland , Helene Knævelsrud , Kristiane Søreng , Benan J Mathai , Alf Håkon Lystad , Serhiy Pankiv , Gunnveig T Bjørndal , Sebastian W Schultz , Viola H Lobert , Robin B Chan , Bowen Zhou , Knut Liestøl , Sven R Carlsson , Thomas J Melia , Gilbert Di Paolo , Anne Simonsen |
2016-12-22 | - |
| 26638075 |
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell Gagan D Gupta , Ãtienne Coyaud , João Gonçalves , Bahareh A Mojarad , Yi Liu , Qianzhu Wu , Ladan Gheiratmand , David Comartin , Johnny M Tkach , Sally W T Cheung , Mikhail Bashkurov , Monica Hasegan , James D Knight , Zhen-Yuan Lin , Markus Schueler , Friedhelm Hildebrandt , Jason Moffat , Anne-Claude Gingras , Brian Raught , Laurence Pelletier |
2015-12-03 |
TANK,
SRA1,
LOC100129118,
TROAP,
PIGK,
WASH1,
DNAJB6,
LOC100506055,
TMEM35B,
OCLN,
LOC100507703,
ERVK3-1,
RBM14-RBM4,
COMMD3-BMI1,
UBA2,
SAE1,
ABCC5,
TIMM23B,
SCAMP2,
SCAMP3,
ARPC3,
ACTR3,
ACTR2,
NUBP2,
TSFM,
RAD50,
KIF20A,
PREB,
ACTR1B,
ACTR1A,
PDIA6,
BCAP31,
SUGP2,
CEBPZ,
ATP6AP2,
LPCAT3,
WASF2,
CDK2,
TENM1,
TXNDC9,
CDK4,
ALG3,
PRMT3,
PSME3,
MPHOSPH9,
CDK5,
TRIM13,
FLOT1,
PSMD14,
MFSD10,
STX6,
DCAF7,
STAM2,
ZMPSTE24,
STUB1,
SIGMAR1,
BET1,
DNAJA2,
PAK4,
KATNB1,
RTN3,
TNIP1,
EMC8,
CNPY2,
TFG,
TUBA1B,
TUBB4A,
TUBB4B,
NDRG1,
NDC80,
NSA2,
PGRMC2,
TUBGCP3,
SEC24B,
EMG1,
MCRS1,
TAB1,
BAIAP2,
PIBF1,
PPIH,
ZNHIT1,
PFDN6,
CLGN,
SLC25A17,
NXF1,
SEC23B,
SEC23A,
VAT1,
NCOA2,
HYOU1,
IPO8,
IPO7,
NEBL,
DCTN2,
PRDX4,
ARL6IP5,
AGPAT1,
RPP38,
CCT7
|
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24705354 |
Hum. Mol. Genet. Stefanie L Butland , Shaun S Sanders , Mandi E Schmidt , Sean-Patrick Riechers , David T S Lin , Dale D O Martin , Kuljeet Vaid , Rona K Graham , Roshni R Singaraja , Erich E Wanker , Elizabeth Conibear , Michael R Hayden |
2014-08-01 | - |
| 23383273 |
PLoS ONE Cheng-Chou Yu , Jyh-Chin Yang , Yen-Ching Chang , Jiing-Guang Chuang , Chung-Wu Lin , Ming-Shiang Wu , Lu-Ping Chow |
2013-01-01 |
PDCD6,
TOM1,
HUWE1,
ARPC2,
CDK4,
CDKN1A,
CDKN1B,
SAP18,
ARIH2,
COG5,
ARFGEF2,
CCT7,
CCT4,
CCT2,
POLR3C,
TAF6L,
CCT8,
STAG2,
SDCCAG3,
TUBGCP2,
RAB10,
YWHAQ,
TMED10,
FERMT2,
CHEK1,
FAF1,
CDC42EP1,
CDC37,
SUPT16H,
PDCD10,
COPE,
HAUS1,
ADD1,
COMT,
CSK,
CSNK2B,
SPC24,
CTNNA1,
CTNND1,
COMMD1,
AP2A2,
AP1B1,
COMMD6,
DYNC1I2,
DSP,
DUSP9,
EIF4A2,
EIF5A,
MARK2,
AKT1,
DDIAS,
BRAT1,
ICK,
RAB3GAP1,
CCT5,
PDXDC1,
TBC1D9B,
GGA2,
WAPL,
NCDN,
WDR43,
NUP205,
MDN1,
RRP12,
SCFD1,
FKBP15,
CLASP1,
UBR4,
NCAPH,
TNPO3,
RBFOX2,
CDC42EP4,
NUP62,
RABGAP1,
MTOR,
RAB3GAP2,
ATXN10,
ARIH1,
COG4,
NEPRO,
CNOT10,
PTPN23,
ULK3,
TBC1D10B,
LRIG1,
DNM3,
APPL1,
GGA1,
KIF1BP,
AMFR,
NBEA,
PDCD4,
UBE2S,
ZNF326,
BZW2,
FHOD1,
GTF3C1,
UBQLN1,
ANXA2
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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