| Type | Description |
|---|---|
| Definition | NOC3 like DNA replication regulator |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:20:00 | Knockdown of human NOC3 in HeLa cells abrogates the chromatin association of other pre-RC proteins including hCDC6 and hMCM, leading to DNA replication defects and eventual apoptosis in an abortive S-phase. Human NOC3 physically interacts with multiple human pre-replicative complex (pre-RC) proteins and associates with known replication origins throughout the cell cycle. | 30741601 |
| 2014-06-07 11:04:00 | We found PLCE1, C11orf92-C11orf93, and NOC3L associated with colorectal cancer susceptibility | 24146276 |
| 2013-06-29 10:03:00 | Results indicate the importance of four gastric cancer susceptibility polymorphisms of IL-10, NOC3L, PSCA and MTRR in the Chinese Han population. | 22796266 |
| 2012-04-26 16:09:00 | A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | 22360420 |
| 2010-01-21 00:00:00 | Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation. | 15564382 |
| Type | IDs |
|---|---|
| Synonymous | AD24, C10orf117, FAD24 |
| Gene |
UniProtKB-ID:
NOC3L_HUMAN
UniprotKB:
Q8WTT2
UniParc:
UPI000006DE09
EMBL:
AK022882,
AK026953,
BC049850,
AB077992,
AL355341
Ensembl:
ENSG00000173145
KO:
hsa:64318
|
| Nucleutide sequences |
EMBL-CDS:
BAB84194.1,
AAH49850.1,
BAB14291.1,
BAB15599.1
Ensembl_TRS:
ENST00000371361
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360412
RefSeq:
XP_016872033.1,
NP_071896.8
|
| Others |
UniRef100:
UniRef100_Q8WTT2
UniRef90:
UniRef90_Q8WTT2
UniRef50:
UniRef50_Q8WTT2
UniGene:
Hs.74899
CCDS:
CCDS7433.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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