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6431 SRSF6

6431

SRSF6

serine and arginine rich splicing factor 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine and arginine rich splicing factor 6

研究结论

Date Results Publications
2020-02-29 10:54:00 Data indicate the extent of inter-individual variation in myocardial dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A)-serine and arginine rich splicing factor 6 (SRSF6)-troponin T2, cardiac type protein (TNNT2) expression in the context of Down syndrome. 31201803
2019-10-12 10:38:00 Results identified SRSF6 protein as one of the factors involved in modulating the splicing of the DDC mutated (c.714+4A>T) transcript. 30260058
2019-01-05 10:08:00 SRSF6 functions the important roles in mediating CRC progression through regulating AS, and indacaterol is repositioned as an antitumour drug through targeting SRSF6. 29114070
2018-05-26 10:56:00 Data suggest that regulation of pancreatic beta-cell function and survival/apoptosis involves alternative splicing modulated by key splicing regulator SRP55; SRP55-regulated alternative splicing includes modulation of function of pro-apoptotic proteins (BIM, BAX), JNK signaling, and endoplasmic reticulum stress. (BIM = BCL-2 interacting protein BIM; BAX = apoptosis regulator BAX) 29246973
2018-01-20 11:45:00 The recent studies suggest that correcting the SRSF6-driven missplicing and/or microtubule-associated imbalance might be of therapeutic value in Huntington's disease. 27529534

名称对应

Type IDs
Synonymous B52, HEL-S-91, SFRS6, SRP55
Gene
UniProtKB-ID: SRSF6_HUMAN
UniprotKB: Q13247
UniParc: UPI000002B37E, UPI00001358C1, UPI000002B37D
EMBL: BC006832, U30883, U30829, AK300411, AL031681, U30828, CH471077
Ensembl: ENSG00000124193
KO: hsa:6431
Nucleutide sequences
EMBL-CDS: AAA93073.1, EAW75967.1, EAW75964.1, AAH06832.1, BAH13279.1, AAA93072.1, AAA93071.1
Ensembl_TRS: ENST00000244020, ENST00000483871
Protein sequencees
Ensembl_PRO: ENSP00000433544, ENSP00000244020
RefSeq: NP_006266.2
Others
UniRef100: UniRef100_Q13247
UniRef90: UniRef90_Q13247
UniRef50: UniRef50_Q13247
UniGene: Hs.725336
CCDS: CCDS13318.1

全选

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研究热度

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