| Type | Description |
|---|---|
| Definition | serine and arginine rich splicing factor 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:23:00 | Antitumor activity of SR splicing-factor 5 knockdown by downregulating pyruvate kinase M2 in non-small cell lung cancer cells. | 31106485 |
| 2019-05-25 12:19:00 | In this study, we uncover an alternative role for the ESCRT-0 component hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) in promoting the constitutive recycling of transmembrane proteins. We find that endosomal localization of the actin nucleating factor Wiscott-Aldrich syndrome protein and SCAR homologue (WASH) requires HRS, which occupies adjacent endosomal subdomains | 29891722 |
| 2019-01-12 11:19:00 | Cold induction of serine and arginine rich splicing factor 5 (SRSF5) is independent of cold-inducible RNA-binding protein (CIRP) and RNA-binding motif protein 3 (RBM3). | 28536481 |
| 2018-12-22 10:37:00 | Study found that SRSF5 is a novel target of SRSF3. SRSF5 is overexpressed in oral squamous cell carcinoma (OSCC) and functions as an oncogene. Its downregulation in OSCC cell lines slows cell growth, cycle progression, and tumor growth. The expression of SRSF5 seems to controlled by an autoregulation mechanism. | 29857020 |
| 2018-12-22 10:08:00 | upon glucose intake, the splicing factor SRSF5 is specifically induced through Tip60-mediated acetylation on K125, which antagonizes Smurf1-mediated ubiquitylation. SRSF5 promotes the alternative splicing of CCAR1 to produce CCAR1S proteins, which promote tumor growth by enhancing glucose consumption and acetyl-CoA production. | 29942010 |
| Type | IDs |
|---|---|
| Synonymous | HRS, SFRS5, SRP40 |
| Gene |
UniProtKB-ID:
SRSF5_HUMAN,
A0A024R6D8_HUMAN,
Q86U32_HUMAN
UniprotKB:
Q13243,
A0A024R6D8,
Q86U32
UniParc:
UPI00001358C0,
UPI000002B37A,
UPI0000D4D1E6,
UPI000000CBDB
EMBL:
BX247988,
BT007089,
AK311805,
BC040209,
AB451250,
U30827,
CR542182,
U30884,
AF020307,
CH471061,
U30826,
CR542167,
BC018823,
BX640605
Ensembl:
ENSG00000100650
KO:
hsa:6430
|
| Nucleutide sequences |
EMBL-CDS:
CAG46979.1,
AAH40209.1,
AAP35752.1,
CAE45711.1,
AAA93074.1,
AAB60405.1,
AAA93070.1,
AAC39543.1,
BAG34748.1,
AAH18823.1,
CAG46964.1,
BAG70064.1,
EAW81005.1,
EAW81002.1,
EAW81006.1,
EAW81004.1,
EAW81007.1,
CAD62322.1,
EAW81009.1
Gene_ORFName:
hCG_21965,
hCG_21965
Ensembl_TRS:
ENST00000553521,
ENST00000553635,
ENST00000557154,
ENST00000394366
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000451088,
ENSP00000377892,
ENSP00000452123,
ENSP00000451391
RefSeq:
XP_016877082.1,
NP_001034554.1,
XP_005268056.1,
XP_005268057.1,
XP_016877083.1,
XP_011535379.1,
NP_001307143.1,
NP_008856.2
|
| Others |
UniRef100:
UniRef100_Q86U32,
UniRef100_Q13243
UniRef90:
UniRef90_Q13243
UniRef50:
UniRef50_Q13243
UniGene:
Hs.632326
CCDS:
CCDS32109.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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