Gprc5b - G protein-coupled receptor, family C, group 5, member B-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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64297 Gprc5b

基因描述

Type	Description
Definition	G protein-coupled receptor, family C, group 5, member B

研究结论

Date	Results	Publications
2020-05-30 13:08:00	GPRC5b is a novel podocyte-specific receptor that regulates inflammatory response in the glomerulus bymodulating the NF-kB signaling pathway.	31285284
2018-11-10 12:17:00	In Gprc5b(-/-) mice, long-term motor learning was impaired in both the rotarod test and the horizontal optokinetic response eye movement (HOKR) test	29481883
2013-12-14 11:26:00	The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex.	24089469
2013-04-27 10:38:00	GPRC5B activates obesity-associated inflammatory signaling in adipocytes.	23169819
2011-11-26 10:36:00	GPRC5B has important roles for animal behavior controlled by the central nervous system.	21840300

名称对应

Type	IDs
Synonymous	AW125761, Raig2
Gene	UniProtKB-ID: GPC5B_MOUSE, D2DFA9_MOUSE UniprotKB: Q923Z0, D2DFA9 UniParc: UPI0001C08B08, UPI0000028EA2 EMBL: FJ529379, AF378831, AC151534, BC020004, AK032047 Ensembl: ENSMUSG00000008734 KO: mmu:64297
Nucleutide sequences	EMBL-CDS: AAK58076.1, AAH20004.1, BAC27669.1, ACU30029.1 Ensembl_TRS: ENSMUST00000008878, ENSMUST00000208394
Protein sequencees	Ensembl_PRO: ENSMUSP00000008878, ENSMUSP00000146777 RefSeq: NP_001182703.1, NP_071865.1
Others	UniRef100: UniRef100_D2DFA9, UniRef100_Q923Z0 UniRef90: UniRef90_Q923Z0 UniRef50: UniRef50_Q923Z0 UniGene: Mm.103439 CCDS: CCDS21777.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
31941358	Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling. Circulation Jorge Carvalho , Ramesh Chennupati , Rui Li , Stefan GÃ¼nther , Harmandeep Kaur , Wencai Zhao , Sarah Tonack , Michael Kurz , Nadja MÃ¶Ãlein , Moritz BÃ¼nemann , Stefan Offermanns , Nina Wettschureck	2020-04-07	-
31285284	GPRC5b Modulates Inflammatory Response in Glomerular Diseases via NF-ÎºB Pathway. J. Am. Soc. Nephrol. Sonia Zambrano , Katja MÃ¶ller-Hackbarth , Xidan Li , Patricia Q Rodriguez , Emmanuelle Charrin , Angelina Schwarz , Jenny NystrÃ¶m , Annika Ãstman Wernerson , Mark Lal , Jaakko Patrakka	2019-09-01	-
30926747	A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype. J Neurosci Dawei Wu , Ira Schieren , Yingzhi Qian , Chaolin Zhang , Thomas M Jessell , Joriene C de Nooij	2019-05-29	-
29481883	Loss of GPRC5B impairs synapse formation of Purkinje cells with cerebellar nuclear neurons and disrupts cerebellar synaptic plasticity and motor learning. Neurosci. Res. Takamitsu Sano , Ayako Kohyama-Koganeya , Masami O Kinoshita , Tetsuya Tatsukawa , Chika Shimizu , Eriko Oshima , Kazuyuki Yamada , Tung Dinh Le , Takumi Akagi , Koujiro Tohyama , Soichi Nagao , Yoshio Hirabayashi	2018-11-01	-
28851741	Gpr158 mediates osteocalcin's regulation of cognition. J. Exp. Med. Lori Khrimian , Arnaud Obri , Mariana Ramos-Brossier , Audrey Rousseaud , StÃ©phanie Moriceau , Anne-Sophie Nicot , Paula Mera , Stylianos Kosmidis , Theodoros Karnavas , Frederic Saudou , Xiao-Bing Gao , Franck Oury , Eric Kandel , Gerard Karsenty	2017-10-02	-
28621310	Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system. Nat Commun H Kaur , J Carvalho , M Looso , P Singh , R Chennupati , J Preussner , S GÃ¼nther , J AlbarrÃ¡n-JuÃ¡rez , D Tischner , S Classen , S Offermanns , N Wettschureck	2017-06-16	-
27626380	High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray	2016-09-22	-
27480124	Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. Xiaoyun Liu , Yan Jiao , Yanhong Cao , Nan Deng , Yonghui Ma , Karen A Hasty , Andrew Kang , Hong Chen , John M Stuart , Weikuan Gu	2016-08-02	-
24952961	A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron Carol L Thompson , Lydia Ng , Vilas Menon , Salvador Martinez , Chang-Kyu Lee , Katie Glattfelder , Susan M Sunkin , Alex Henry , Christopher Lau , Chinh Dang , Raquel Garcia-Lopez , Almudena Martinez-Ferre , Ana Pombero , John L R Rubenstein , Wayne B Wakeman , John Hohmann , Nick Dee , Andrew J Sodt , Rob Young , Kimberly Smith , Thuc-Nghi Nguyen , Jolene Kidney , Leonard Kuan , Andreas Jeromin , Ajamete Kaykas , Jeremy Miller , Damon Page , Geri Orta , Amy Bernard , Zackery Riley , Simon Smith , Paul Wohnoutka , Michael J Hawrylycz , Luis Puelles , Allan R Jones	2014-07-16	-
24089469	The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex. Development Nobuhiro Kurabayashi , Minh Dang Nguyen , Kamon Sanada	2013-11-01	Gprc5a, Gprc5b, Gprc5c

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