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64282 TENT4B

64282

TENT4B

terminal nucleotidyltransferase 4B

protein-coding

Homo sapiens

基因描述

Type Description
Definition terminal nucleotidyltransferase 4B

研究结论

Date Results Publications
2020-10-31 13:20:00 Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing. 32451488
2019-10-19 10:54:00 We find that mature hTR derives from extended precursors but that in PARN-mutant cells hTR maturation kinetically stalls and unprocessed precursors are degraded. Loss of poly(A)polymerase PAPD5 in PARN-mutant cells accelerates hTR maturation and restores hTR processing, indicating that oligoadenylation and deadenylation set rates of hTR maturation 30930056
2018-09-08 10:49:00 TENT4A and TENT4B produce a mixed tail that shields mRNA from rapid deadenylation. 30026317
2017-11-11 11:38:00 A novel post-transcriptional regulatory network involving carbohydrate metabolism and glucose homeostasis mediated by GLD4. 28383716
2017-05-07 01:29:00 We analyzed the interactions of the human TRAMP-like proteins, PAPD5, ZCCHC7, and MTR4, with the nuclear exosome. PAPD5 and ZCCHC7 exhibited mutual interactions in presence of the exosome catalytic subunit RRP6, whereas MTR4 was dispensable for their assembly 27434818

名称对应

Type IDs
Synonymous PAPD5, TRF4-2, TUT3
Gene
UniProtKB-ID: PAPD5_HUMAN, A0A024R6Q7_HUMAN
UniprotKB: Q8NDF8, A0A024R6Q7
UniParc: UPI00004C2D36, UPI00004C2D37, UPI0000EE5860, UPI00004C2CEA, UPI00004C2D35, UPI00017A7DC6
EMBL: CH471092, AK001141, AL833922, AK300918, AC007597, AF089897, AK097589, AC007610
Ensembl: ENSG00000121274
KO: hsa:64282
Nucleutide sequences
EMBL-CDS: CAD38778.1, BAA91518.1, AAD45199.1, BAG62550.1, EAW82748.1, EAW82747.1
Gene_ORFName: hCG_24891
Ensembl_TRS: ENST00000436909
Protein sequencees
Ensembl_PRO: ENSP00000396995
RefSeq: XP_011521580.1, XP_005256150.2, NP_001035374.2, XP_011521577.1, NP_001352253.1, NP_001352252.1, XP_011521578.1, NP_001035375.2
Others
UniRef100: UniRef100_Q8NDF8, UniRef100_A0A024R6Q7
UniRef90: UniRef90_Q8NDF8, UniRef90_A0A024R6Q7
UniRef50: UniRef50_Q8NDF8, UniRef50_Q8NDF8-2
UniGene: Hs.514342
CCDS: CCDS54006.1

全选

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研究热度

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