| Type | Description |
|---|---|
| Definition | serine and arginine rich splicing factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | SRSF3 Is a Critical Requirement for Inclusion of Exon 3 of BIS Pre-mRNA. | 33086735 |
| 2021-03-13 13:24:00 | B7-H3 is spliced by SRSF3 in colorectal cancer. | 32719950 |
| 2021-03-06 13:27:00 | Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3. | 33141183 |
| 2020-06-20 11:18:00 | Results have identified SRSF3 as the trans-RNA splicing factor responsible for mediating alternative RNA splicing (AS) of CPEB2 through inclusion of exon 4 via binding at the cis-RNA pentameric exonic splicing enhancers. These findings demonstrate that SRSF3 modulates CPEB2 AS to induce the expression of the CPEB2B isoform that drives TNBC phenotypes correlating with aggressive human breast cancer. | 31138601 |
| 2020-06-06 12:11:00 | SRSF3 was frequently upregulated in clinical glioma specimens and was associated with tumor progression and poor prognosis. SRSF3 expression promoted cell proliferation, self-renewal, and tumorigenesis. Transcriptomic profiling found more than 1,000 SRSF3-affected alternative splicing events. SRSF3-regulated AS of ETV1 and NDE1 markedly increased their oncogenic activity in GSCs. | 31462429 |
| Type | IDs |
|---|---|
| Synonymous | SFRS3, SRp20 |
| Gene |
UniProtKB-ID:
SRSF3_HUMAN,
B2R6F3_HUMAN
UniprotKB:
P84103,
B2R6F3
UniParc:
UPI000002B379,
UPI0000004131
EMBL:
AK304097,
CH471081,
BT007017,
GQ891426,
AK312553,
AB451229,
Z85986,
AF107405,
BC069018,
L10838,
BC000914,
AB451352
Ensembl:
ENSG00000112081
KO:
hsa:6428
|
| Nucleutide sequences |
EMBL-CDS:
AAH69018.1,
AAH00914.1,
AAA36648.1,
AAP35663.1,
EAX03898.1,
BAG65003.1,
AAD44523.1,
BAG35450.1,
EAX03903.1,
BAG70043.1,
ADO22288.1,
EAX03901.1,
BAG70166.1
Gene_ORFName:
hCG_14802
Ensembl_TRS:
ENST00000620941,
ENST00000477442,
ENST00000373715
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362820,
ENSP00000436036,
ENSP00000482833
RefSeq:
NP_003008.1
|
| Others |
UniRef100:
UniRef100_P84103
UniRef90:
UniRef90_P84103
UniRef50:
UniRef50_P84103
UniGene:
Hs.405144
CCDS:
CCDS4823.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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