| Type | Description |
|---|---|
| Definition | eph receptor A4a |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 10:07:00 | The authors show that forward signaling of EphA4 is required for border sharpening and induction of boundary cells in the zebrafish hindbrain, which they find both require kinase-dependent signaling, with a lesser input of PDZ domain-dependent signaling. | 31502954 |
| 2018-10-27 11:29:00 | In myelinating co-cultures and in zebrafish, we find that the number of mature oligodendrocytes does not change as result of manipulating signaling through the ephrinA1-EphA4 system. However, in both systems, inhibition of EphA4 signaling leads to a higher number of myelin sheaths formed by each oligodendrocyte. In isolated oligodendrocyte cultures, activation of EphA4 reduced process extension. | 29350423 |
| 2014-05-31 10:28:00 | Downregulation of EphA4a compromises actomyosin cables and cells with different rhombomeric identity intermingle, and the phenotype is rescued enhancing myosin II activity. | 24569501 |
| 2010-01-21 00:00:00 | EphA4 is required for cell adhesion and rhombomere-boundary formation in the zebrafish. | 15797022 |
| 2010-01-21 00:00:00 | Data show that EfnB2a is required in developing hindbrain for normal cell affinity and that EphA4 and EfnB2a regulate cell affinity independently within their respective rhombomeres. | 19135438 |
| Type | IDs |
|---|---|
| Synonymous | EphA4, apha3, cb246, ek2, epha3, rtk1, sb:cb246, zek2, zgc:109882 |
| Gene |
UniProtKB-ID:
Q5ZEW1_DANRE
UniprotKB:
Q5ZEW1
UniParc:
UPI000044F1A7
EMBL:
AJ849304
KO:
dre:64271
|
| Nucleutide sequences |
EMBL-CDS:
CAH60717.1
|
| Protein sequencees |
RefSeq:
NP_001005919.2,
XP_009296987.1,
XP_005171375.1,
XP_005171373.1,
XP_005171372.1,
XP_005171374.1,
NP_001352100.1
|
| Others |
UniRef100:
UniRef100_Q5ZEW1
UniRef90:
UniRef90_Q5ZEW1
UniRef50:
UniRef50_Q03137
UniGene:
Dr.47585
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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