| Type | Description |
|---|---|
| Definition | serine and arginine rich splicing factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity. | 32332923 |
| 2020-11-21 13:33:00 | Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia. | 32358566 |
| 2020-08-22 15:29:00 | Modulation of SRSF2 expression reverses the exhaustion of TILs via the epigenetic regulation of immune checkpoint molecules. | 31838573 |
| 2020-08-01 12:15:00 | these data are the first to demonstrate expression of the CSF3R-V3 splice variant in primary human myeloid cells and a role for SRSF2 in modulating CSF3R splicing | 31462738 |
| 2020-08-01 10:47:00 | mutations in SF3B1, U2AF1, and SRSF2 enhance NFkappaB activity and LPS-induced inflammatory cytokine production in macrophages, patient-derived cell lines, and mouse and human myeloid cells | 30846499 |
| Type | IDs |
|---|---|
| Synonymous | PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b |
| Gene |
UniProtKB-ID:
SRSF2_HUMAN,
Q53FN0_HUMAN,
A0A024R8U5_HUMAN
UniprotKB:
Q01130,
Q53FN0,
A0A024R8U5
UniParc:
UPI0000000C2A,
UPI000050A919,
UPI0000E03AC6
EMBL:
BC070086,
AC005837,
AK297813,
CH471099,
X75755,
BC000339,
M90104,
AK124792,
AK223252,
BC001303,
L03693,
X62447,
BT007250
Ensembl:
ENSG00000161547
KO:
hsa:6427
|
| Nucleutide sequences |
EMBL-CDS:
AAA60306.1,
BAG60151.1,
AAA60162.1,
AAP35914.1,
CAA53383.1,
CAA44307.1,
AAH01303.1,
BAG54097.1,
EAW89439.1,
AAH70086.1,
AAH00339.1,
EAW89448.1,
BAD96972.1,
EAW89447.1,
EAW89440.1,
EAW89445.1
Gene_ORFName:
hCG_27842
Ensembl_TRS:
ENST00000508921,
ENST00000452355,
ENST00000392485,
ENST00000359995,
ENST00000585202
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000462425,
ENSP00000391278,
ENSP00000353089,
ENSP00000441780,
ENSP00000376276
RefSeq:
XP_016880431.1,
NP_003007.2,
NP_001182356.1
|
| Others |
UniRef100:
UniRef100_Q53FN0,
UniRef100_Q01130
UniRef90:
UniRef90_Q01130,
UniRef90_Q53FN0
UniRef50:
UniRef50_Q01130,
UniRef50_Q06A98
UniGene:
Hs.584801
CCDS:
CCDS11749.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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