| Type | Description |
|---|---|
| Definition | membrane spanning 4-domains A6A |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 11:30:00 | Meta analysis validated the Alzheimer disease protective association for MS4A6A (rs610932) variants. | 29504051 |
| 2018-03-31 11:55:00 | rs610932 MS4A6A is not associated with late-onset Alzheimer's disease. | 28477215 |
| 2018-02-03 10:30:00 | these findings reveal that MS4A6A genotypes affect Alzheimer's disease specific brain structures | 27244883 |
| 2017-10-07 11:30:00 | Study found enrichment of epistasis in gonadotropin-releasing hormone signaling with risk single-nucleotide polymorphisms in APOE and MS4A6A. Results suggest that in addition to APOE, MS4A6A polymorphisms should be considered in hormone trials targeting gonadotropins. | 27337227 |
| 2017-09-23 12:43:00 | Its mutation plays a role in pathogenesis of Alzheimer's disease. | 27084067 |
| Type | IDs |
|---|---|
| Synonymous | 4SPAN3, 4SPAN3.2, CD20L3, CDA01, MS4A6, MST090, MSTP090 |
| Gene |
UniProtKB-ID:
M4A6A_HUMAN,
A0A024R516_HUMAN,
A0A024R554_HUMAN,
B4DUN6_HUMAN,
E9PSA9_HUMAN
UniprotKB:
Q9H2W1,
A0A024R516,
A0A024R554,
B4DUN6,
E9PSA9
UniParc:
UPI0000072702,
UPI00017A7F2F,
UPI0000047616,
UPI0001F77AB4,
UPI00001B57D1,
UPI0000D4D7A1,
UPI0000047617
EMBL:
AF237908,
AP003970,
AF286866,
AK300725,
BC022854,
AF212240,
AF142409,
AB013104,
AF253977,
AF350503,
CH471076,
AK291870,
AF261136,
AF350502,
AF172819,
AF354930
Ensembl:
ENSG00000110077
KO:
hsa:64231
|
| Nucleutide sequences |
EMBL-CDS:
AAK37994.1,
AAL56222.1,
AAL07357.1,
AAK37417.1,
AAG44672.1,
AAQ13613.1,
BAB18740.1,
BAF84559.1,
AAG44626.1,
AAH22854.1,
AAL56223.1,
AAG41780.1,
AAG27920.1,
EAW73867.1,
EAW73866.1,
EAW73870.1,
EAW73868.1,
BAG62398.1
Gene_ORFName:
MSTP090,
CDA01,
hCG_40405,
hCG_40405
Ensembl_TRS:
ENST00000528851,
ENST00000412309,
ENST00000532169,
ENST00000530839,
ENST00000426738,
ENST00000420732,
ENST00000529054
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403212,
ENSP00000431266,
ENSP00000431901,
ENSP00000436979,
ENSP00000392921,
ENSP00000392770,
ENSP00000435844
RefSeq:
NP_001317204.1,
NP_690590.1,
XP_024304423.1,
XP_024304422.1,
XP_024304421.1,
NP_690591.1,
XP_024304420.1,
XP_006718723.1,
NP_001234928.1,
NP_071744.2,
XP_016873614.1,
XP_005274234.1,
XP_006718724.1,
XP_011543511.1
|
| Others |
UniRef100:
UniRef100_A0A024R516,
UniRef100_B4DUN6,
UniRef100_Q9H2W1
UniRef90:
UniRef90_Q9H2W1,
UniRef90_A0A2I2YXU6
UniRef50:
UniRef50_Q9H2W1,
UniRef50_Q9H2W1-3
UniGene:
Hs.523702,
Hs.744932
CCDS:
CCDS44615.1,
CCDS58134.1,
CCDS44616.1,
CCDS7981.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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