| Type | Description |
|---|---|
| Definition | praja ring finger ubiquitin ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:05:00 | Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFbeta Signaling. | 32127355 |
| 2011-10-22 11:23:00 | Data provide clues into novel aspects of Praja1 function. | 21461837 |
| 2011-07-30 11:05:00 | these results suggest a role for PRAJA1 in regulating the level of PRC2 by targeting its free subunits for Ub-mediated proteasomal degradation. | 21513699 |
| 2010-01-21 00:00:00 | Involved in protein ubiquitination in the brain. Candidate gene for X-linked mental retardation. | 12036302 |
| 2010-01-21 00:00:00 | A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1. | 11959851 |
| Type | IDs |
|---|---|
| Synonymous | PRAJA1, RNF70 |
| Gene |
UniProtKB-ID:
PJA1_HUMAN
UniprotKB:
Q8NG27
UniParc:
UPI00005B2DFB,
UPI000006D00A,
UPI00000714A3
EMBL:
CH471132,
AF262024,
BC048323,
AL157699,
BC075803,
AF264620,
BC105051,
AK021892,
BC105053
Ensembl:
ENSG00000181191
KO:
hsa:64219
|
| Nucleutide sequences |
EMBL-CDS:
AAM53040.1,
AAI05052.1,
AAM53039.1,
EAX05367.1,
AAI05054.1,
BAB13928.1,
AAH48323.1,
AAH75803.1
Ensembl_TRS:
ENST00000374583,
ENST00000374571,
ENST00000361478,
ENST00000374584
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355014,
ENSP00000363711,
ENSP00000363699,
ENSP00000363712
RefSeq:
NP_660095.1,
NP_001369704.1,
NP_001027568.1,
NP_001369705.1,
NP_071763.2
|
| Others |
UniRef100:
UniRef100_Q8NG27
UniRef90:
UniRef90_Q8NG27
UniRef50:
UniRef50_O55176
UniGene:
Hs.522679
CCDS:
CCDS35316.1,
CCDS14392.1,
CCDS14393.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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