| Type | Description |
|---|---|
| Definition | transcription factor B2, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | Phosphorylation of mitochondrial transcription factor B2 controls mitochondrial DNA binding and transcription. | 32505352 |
| 2019-05-18 12:18:00 | a rare homozygous c.790C>T (His264Tyr) variation in TFB2M gene in two Korean siblings with autism spectrum disorder by whole-exome sequencing, is reported. | 30414672 |
| 2017-12-16 11:48:00 | Study reports crystal structures of human mitochondrial transcription initiation complexes assembled on both light and heavy strand promoters. The structures reveal how transcription factors TFAM and TFB2M assist mitochondrial RNA polymerase to achieve promoter-dependent initiation. | 29149603 |
| 2017-07-08 11:46:00 | demonstrate that a complex composed of TFAM and POLRMT was readily formed at the promoter but alone was insufficient for promoter melting, which only occurred when TFB2M joined the complex | 28028173 |
| 2014-06-28 12:45:00 | The results reveal the organization of TFAM, POLRMT and TFB2M around the light-strand promoter and represent the first structural characterization of the entire mitochondrial transcriptional initiation complex. | 24413562 |
| Type | IDs |
|---|---|
| Synonymous | Hkp1, mtTFB2 |
| Gene |
UniProtKB-ID:
TFB2M_HUMAN
UniprotKB:
Q9H5Q4
UniParc:
UPI0000073CFC
EMBL:
AF529366,
AL356583,
BC003383,
AK026835,
AK026314
Ensembl:
ENSG00000162851
KO:
hsa:64216
|
| Nucleutide sequences |
EMBL-CDS:
BAB15566.1,
BAB15441.1,
AAH03383.1,
AAQ09600.1
Ensembl_TRS:
ENST00000366514
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355471
RefSeq:
NP_071761.1,
XP_011542550.1,
XP_016857544.1
|
| Others |
UniRef100:
UniRef100_Q9H5Q4
UniRef90:
UniRef90_Q9H5Q4
UniRef50:
UniRef50_Q9H5Q4
UniGene:
Hs.7395
CCDS:
CCDS1627.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员