| Type | Description |
|---|---|
| Definition | tryptophan 2,3-dioxygenase |
| Date | Results | Publications |
|---|---|---|
| 2015-01-24 11:29:00 | Results show that stress-induced corticosterone and consequent activation of hepatic TDO, tryptophan metabolism and production of kynurenine provoke a depression-related behavioural phenotype | 24472498 |
| 2011-12-14 17:49:00 | tryptophan oxygenase gene might rely on the binding of the enhancer (the -8.5kb S/MAR-GRE) and the promoter to the inner nuclear matrix. | 19632204 |
| 2011-12-12 13:21:00 | Data support the involvement of insulin in modulation of glucocorticoid receptor signaling pathway which mediates, in part, the activity of tryptophan oxygenase. | 17223727 |
| 2010-10-04 12:33:00 | these data show that the nucleosome array in the regulatory region of the actively transcribed tdo gene in vivo is disturbed. | 20737904 |
| 2010-01-21 00:00:00 | The cerebrocortical TDO2 genes were increased in aged rats. Certain age dependent transcriptional changes might influence the mechanism of Alzheimer dis and other neurodegenerative disorders. | 19835274 |
| Type | IDs |
|---|---|
| Synonymous | TO, Tdo |
| Gene |
UniProtKB-ID:
T23O_RAT
UniprotKB:
P21643
UniParc:
UPI00001367B8
EMBL:
M55167,
X01849,
X60833,
X05145,
BC089802
Ensembl:
ENSRNOG00000011612
KO:
rno:64206
|
| Nucleutide sequences |
EMBL-CDS:
AAA63503.1,
AAH89802.1,
CAA25974.1,
CAA28794.1
Ensembl_TRS:
ENSRNOT00000015732
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015732
RefSeq:
NP_071798.1
|
| Others |
UniRef100:
UniRef100_P21643
UniRef90:
UniRef90_P21643
UniRef50:
UniRef50_P48775
UniGene:
Rn.1029
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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