| Type | Description |
|---|---|
| Definition | SET domain and mariner transposase fusion gene |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:57:00 | The roles of the human SETMAR protein in illegitimate DNA recombination and non-homologous end joining repair were studied. Contrary to previous reports, it was found that wild type SETMAR had little to no effect on the rate of cell division, DNA integration into the genome or non-homologous end joining. | 31238295 |
| 2019-08-24 12:52:00 | ur data is consistent with a model in which SETMAR is part of an anthropoid primate-specific regulatory network centered on the subset of genes containing a transposon end. | 30329085 |
| 2018-02-24 11:22:00 | Various SETMAR proteins can be synthesized in human glioblastoma that may each have specific biophysical and/or biochemical properties and characteristics. | 28038463 |
| 2017-06-10 12:26:00 | These results suggest that Metnase enhances Exo1-mediated exonuclease activity on the lagging strand DNA by facilitating Exo1 loading onto a single strand gap at the stalled replication fork. | 27974460 |
| 2016-06-28 10:46:00 | The SET domain is needed for the 5' end of ss-overhang cleavage with fork and non-fork DNA without affecting the Metnase-DNA interaction. This domain has a positive role in restart of replication fork and the 5' end of ss-overhang cleavage. | 26437079 |
| Type | IDs |
|---|---|
| Synonymous | METNASE, Mar1 |
| Gene |
UniProtKB-ID:
SETMR_HUMAN,
Q96H41_HUMAN,
B4DND2_HUMAN
UniprotKB:
Q53H47,
Q96H41,
B4DND2
UniParc:
UPI000066D9D9,
UPI00001BD988,
UPI000198C88D,
UPI00017A77D2,
UPI0000E5A460
EMBL:
AY952295,
BC008931,
AK222734,
AK302296,
U52077,
AC023483,
DQ341316,
AK297865,
BC011635,
AC034191
Ensembl:
ENSG00000170364
KO:
hsa:6419
|
| Nucleutide sequences |
EMBL-CDS:
BAG63636.1,
AAC52010.1,
AAH11635.1,
ABC72087.1,
AAY29570.1,
BAD96454.1,
AAH08931.2,
BAG60194.1
Ensembl_TRS:
ENST00000425863,
ENST00000430981,
ENST00000358065
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403000,
ENSP00000403145,
ENSP00000373354
RefSeq:
NP_006506.3,
NP_001307605.1,
NP_001307607.1,
XP_006713357.1,
XP_006713355.1,
NP_001230652.1,
NP_001307606.1,
NP_001263254.1
|
| Others |
UniRef100:
UniRef100_B4DND2,
UniRef100_Q53H47,
UniRef100_Q96H41
UniRef90:
UniRef90_Q53H47,
UniRef90_B4DND2,
UniRef90_Q96H41
UniRef50:
UniRef50_Q96H41,
UniRef50_Q53H47
UniGene:
Hs.475300
CCDS:
CCDS58814.1,
CCDS2563.2,
CCDS63528.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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