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64177 Trpv6

64177

Trpv6

transient receptor potential cation channel, subfamily V, member 6

protein-coding

Mus musculus

基因描述

Type Description
Definition transient receptor potential cation channel, subfamily V, member 6

研究结论

Date Results Publications
2021-01-23 13:03:00 The calcium channel TRPV6 is a novel regulator of RANKL-induced osteoclastic differentiation and bone absorption activity through the IGF-PI3K-AKT pathway. 33159483
2020-10-24 14:09:00 Variants That Affect Function of TRPV6 Are Associated With Early-Onset Chronic Pancreatitis. 31930989
2020-10-24 13:56:00 Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption. 31013259
2020-07-25 13:02:00 Net TRPV6-mediated Ca(2+) flux across the duodenum was absent in pre-weaned (P14) mice but present after weaning. In contrast, authors found significant transcellular Ca(2+) absorption in the jejunum at 2 weeks but not 2 months of age. 31398491
2020-07-18 11:30:00 results show that TRPV6 is necessary for the Ca(2+) uptake in trophoblasts and that TRPV6 deficiency in the placenta leads to reduced embryo growth, minor bone calcification, and impaired bone development. 30786075

名称对应

Type IDs
Synonymous CAT, CaT1, Cac, Ecac2, Otrpc3
Gene
UniProtKB-ID: TRPV6_MOUSE
UniprotKB: Q91WD2
UniParc: UPI00059ACEA1
EMBL: AK077234, BC016101, AJ542487
KO: mmu:64177
Nucleutide sequences
EMBL-CDS: CAD62684.1, BAC36699.1, AAH16101.1
Protein sequencees
RefSeq: NP_071858.3
Others
UniRef100: UniRef100_Q91WD2
UniRef90: UniRef90_Q9R186
UniRef50: UniRef50_Q9H1D0
UniGene: Mm.296889
CCDS: CCDS20052.2

全选

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研究热度

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