| Type | Description |
|---|---|
| Definition | spectrin, alpha, non-erythrocytic 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 10:10:00 | alphaII spectrin has a role in critical aspects of dendritic and axonal development and synaptogenesis, and there is a dominant-negative mechanism of SPTAN1 mutations in epileptic encephalopathy | 29337302 |
| 2018-10-27 11:08:00 | These findings reveal spectrin (alpha/beta) / ankyrin B cytoskeletal and signaling proteins as key regulators of T-type calcium channels expressed in the nervous system. | 29720258 |
| 2012-12-22 10:46:00 | The present study demonstrates the age-dependent intraneuronal presence of an alphaII-spectrin cleavage fragment in mammalian forebrain which is exacerbated in a transgenic model of AD. | 22723836 |
| 2010-11-27 11:00:00 | the embryonic mammalian heart expresses a significant amount of alpha II-spectrin with a reduced avidity for beta-spectrin and the ability to promote myocyte growth | 20114050 |
| 2010-11-06 11:00:00 | Results indicate that the phosphorylation-dependent interaction between 14-3-3beta and alphaII spectrin acts as a switch between positive and negative regulation of neurite outgrowth stimulated by NCAM. | 20598904 |
| Type | IDs |
|---|---|
| Synonymous | A2a, IPF, Spna2 |
| Gene |
UniProtKB-ID:
SPTN1_RAT,
A0A0G2K1Y8_RAT,
Q6IRK8_RAT
UniprotKB:
P16086,
A0A0G2K1Y8,
Q6IRK8
UniParc:
UPI0000376008,
UPI0003D07523,
UPI0000135DB8
EMBL:
AF084186,
X90845,
AC128578,
J04828,
BC070885
Ensembl:
ENSRNOG00000015396
KO:
rno:64159
|
| Nucleutide sequences |
EMBL-CDS:
AAA40770.1,
CAA62350.1,
AAC33127.1,
AAH70885.1
Ensembl_TRS:
ENSRNOT00000045827,
ENSRNOT00000091697,
ENSRNOT00000082672
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000042382,
ENSRNOP00000072038,
ENSRNOP00000068710
RefSeq:
XP_008759897.1,
XP_008759899.1,
XP_008759895.1,
XP_008759898.1,
XP_008759900.1,
XP_008759896.1,
NP_741984.3
|
| Others |
UniRef100:
UniRef100_Q6IRK8,
UniRef100_P16086,
UniRef100_A0A0G2K1Y8
UniRef90:
UniRef90_Q6IRK8,
UniRef90_Q13813
UniRef50:
UniRef50_P16546-2,
UniRef50_Q13813
UniGene:
Rn.5812
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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