| Type | Description |
|---|---|
| Definition | peptide deformylase, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 10:58:00 | compound M7594_0037 exhibited potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 muM, respectively. Molecular docking studies suggested that M7594_0037 and its three derivatives could interact with Human peptide deformylase by several conserved hydrogen bonds. | 27023495 |
| 2015-05-23 10:45:00 | c-myc regulated the expression of human PDF. | 24675470 |
| 2013-11-30 10:47:00 | This is the first report showing that PDF is over-expressed in breast, colon, and lung cancers | 23815882 |
| 2012-08-18 10:43:00 | these data reveals that PDF has several transcription start sites, the most important of which only 18 bp from the initiation codon. | 22554513 |
| 2012-03-17 10:31:00 | the origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process. | 21805148 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DEFM_HUMAN,
A0A024R6Y3_HUMAN
UniprotKB:
Q9HBH1,
A0A024R6Y3
UniParc:
UPI000003C676
EMBL:
CH471092,
AF322879,
BC019912,
AF239156
Ensembl:
ENSG00000258429
KO:
hsa:64146
|
| Nucleutide sequences |
EMBL-CDS:
AAG33968.1,
AAK15624.1,
AAH19912.1,
EAW83268.1,
EAW83265.1
Gene_ORFName:
hCG_2027080
Ensembl_TRS:
ENST00000288022
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000288022
RefSeq:
NP_071736.1
|
| Others |
UniRef100:
UniRef100_Q9HBH1
UniRef90:
UniRef90_Q9HBH1
UniRef50:
UniRef50_Q9HBH1
UniGene:
Hs.130849
CCDS:
CCDS10875.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员