| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily G member 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:00:00 | Regulation of ABCG4 transporter expression by sterols and LXR ligands. | 33141061 |
| 2019-11-23 10:43:00 | Alix serves as a co-factor for the interaction between the E3-ubiquitin ligase NEDD4-1 and the ABC transporter targets, ABCG1 and ABCG4. | 31159502 |
| 2019-11-09 11:46:00 | Intriguingly, DU-145 cells with stably depleted ABCG4 levels not only significantly delayed the development of the tumor but also greatly sensitized the tumor to a low dose of doxorubicin that resulted in complete tumor regression. Collectively, this data reinforces a novel function of ABCG4 in doxorubicin-mediated chemoresistance, and as a potential therapeutic target in drug-induced prostate cancer chemoresistance. | 30834613 |
| 2019-07-06 12:13:00 | We show for the first time that Abcg4 may function in vivo to export Abeta at the BBB, in a process that can be antagonized by its putative natural ligand, desmosterol (and possibly cholesterol). | 29042617 |
| 2017-11-04 13:11:00 | Modulation of miR-185-5p expression by EBV-miR-BART6 contributes to developmental differences in ABCG4 gene expression in human megakaryocytes | 27816548 |
| Type | IDs |
|---|---|
| Synonymous | WHITE2 |
| Gene |
UniProtKB-ID:
ABCG4_HUMAN
UniprotKB:
Q9H172
UniParc:
UPI000000D999,
UPI00042DB66E,
UPI00042DB667,
UPI00042DB660
EMBL:
AY055472,
CH471065,
AK290035,
AJ308237,
AJ300465,
BC041091,
AK289830
Ensembl:
ENSG00000172350
KO:
hsa:64137
|
| Nucleutide sequences |
EMBL-CDS:
AAL16401.1,
EAW67465.1,
BAF82724.1,
EAW67464.1,
CAC87131.1,
EAW67466.1,
AAH41091.1,
CAC17140.1,
AAL16402.1,
AAL16400.1,
BAF82519.1
Ensembl_TRS:
ENST00000622721,
ENST00000615496,
ENST00000619701
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479253,
ENSP00000484289,
ENSP00000481728
RefSeq:
XP_011541254.1,
NP_071452.2,
NP_001335121.1,
NP_001135977.1,
NP_001335120.1
|
| Others |
UniRef100:
UniRef100_Q9H172
UniRef90:
UniRef90_Q9H172
UniRef50:
UniRef50_Q9H172
UniGene:
Hs.126378
CCDS:
CCDS8415.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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