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64121 RRAGC

64121

RRAGC

Ras related GTP binding C

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ras related GTP binding C

研究结论

Date Results Publications
2021-03-13 13:17:00 The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both and Growth Factor Restriction. 32898476
2021-02-06 13:55:00 Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. 33340489
2021-02-02 13:27:00 Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. 32868926
2020-05-02 10:58:00 cryo-electron microscopy structure of RagA/RagC in complex with mTORC1 shows the details of RagA/RagC binding to the RAPTOR subunit of mTORC1 and explains why only the RagAGTP/RagCGDP nucleotide state binds mTORC1 31601764
2020-04-25 11:51:00 The Raptor alpha-solenoid directly detects the nucleotide state of RagA while the Raptor "claw" threads between the GTPase domains to detect that of RagC. Mutations that disrupted Rag-Raptor binding inhibited mTORC1 lysosomal localization and signaling. 31601708

名称对应

Type IDs
Synonymous GTR2, RAGC, TIB929
Gene
UniProtKB-ID: RRAGC_HUMAN, B4DQ03_HUMAN, B4DQG4_HUMAN
UniprotKB: Q9HB90, B4DQ03, B4DQG4
UniParc: UPI00017A76EF, UPI00000372EF, UPI00017A7868
EMBL: AK298573, AF272035, AL139260, AK298788, AK023373, AF323609, BC016668
Ensembl: ENSG00000116954
KO: hsa:64121
Nucleutide sequences
EMBL-CDS: BAB14548.1, AAG32662.1, AAH16668.1, AAG45221.1, BAG60765.1, BAG60926.1
Ensembl_TRS: ENST00000373001
Protein sequencees
Ensembl_PRO: ENSP00000362092
RefSeq: NP_001258780.1, NP_071440.1
Others
UniRef100: UniRef100_Q9HB90, UniRef100_B4DQG4, UniRef100_B4DQ03
UniRef90: UniRef90_B4DQ03, UniRef90_Q9HB90
UniRef50: UniRef50_Q9HB90, UniRef50_B4DQ03
UniGene: Hs.532461
CCDS: CCDS430.1

全选

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