| Type | Description |
|---|---|
| Definition | modulator of apoptosis 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:47:00 | both in vitro and in vivo data presented strongly support the conclusion that MOAP-1 is an important apoptotic modulator in ischemic injury. These results may suggest that a reduction of MOAP-1 function in the brain could be a potential therapeutic approach in the treatment of acute stroke. | 30132384 |
| 2020-04-18 12:20:00 | Results indicate that MOAP1 is a downstream target of miR-92a in colorectal cancer cells. | 31064356 |
| 2018-07-14 11:04:00 | RACK1 associates with MOAP-1 via electrostatic associations similar to those observed between MOAP-1/RASSF1A and MOAP-1/TNF-R1. These events illustrate the complex nature of MOAP-1 regulation and characterizes the important role of the scaffolding protein, RACK1, in influencing MOAP-1 biology. | 29470995 |
| 2017-11-26 00:01:00 | These findings reveal a role for MOAP-1 in Fas signaling in the liver by promoting MTCH2-mediated tBid recruitment to mitochondria. | 27320914 |
| 2017-09-02 13:01:00 | UBR5 downregulates proapoptotic MOAP-1 and suggest that UBR5 can confer cisplatin resistance in ovarian cancer. | 27721409 |
| Type | IDs |
|---|---|
| Synonymous | MAP-1, PNMA4 |
| Gene |
UniProtKB-ID:
MOAP1_HUMAN
UniprotKB:
Q96BY2
UniParc:
UPI0000037797
EMBL:
AK315522,
AF305550,
AK024029,
BC015044,
CH471061
Ensembl:
ENSG00000165943,
ENSG00000278268
KO:
hsa:64112
|
| Nucleutide sequences |
EMBL-CDS:
AAG31786.1,
EAW81516.1,
BAB14788.1,
BAG37903.1,
AAH15044.1
Ensembl_TRS:
ENST00000616515,
ENST00000298894,
ENST00000556883,
ENST00000627896
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482284,
ENSP00000486260,
ENSP00000451594,
ENSP00000298894
RefSeq:
NP_071434.2
|
| Others |
UniRef100:
UniRef100_Q96BY2
UniRef90:
UniRef90_Q96BY2
UniRef50:
UniRef50_Q96BY2
UniGene:
Hs.24719
CCDS:
CCDS9908.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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