| Type | Description |
|---|---|
| Definition | BLM RecQ like helicase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma. | 33318203 |
| 2021-01-23 12:58:00 | iPSC line derived from a Bloom syndrome patient retains an increased disease-specific sister-chromatid exchange activity. | 31918214 |
| 2020-12-12 13:23:00 | Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach. | 32704157 |
| 2020-06-06 11:19:00 | BLM can neither associate with nor translocate on ssDNA that is bound by the recombinase protein RAD51. Moreover, these data reveal that the presence of RAD51 also blocks BLM translocation on dsDNA substrates and potential regulator roles for BLM helicase during DNA replication and repair. | 31544923 |
| 2020-05-09 11:24:00 | These results reveal that BLM limits interferon-stimulated gene induction, thus connecting DNA damage to cellular innate immune response, which may contribute to human pathogenesis. | 30936263 |
| Type | IDs |
|---|---|
| Synonymous | BS, MGRISCE1, RECQ2, RECQL2, RECQL3 |
| Gene |
UniProtKB-ID:
BLM_HUMAN,
H0YNU5_HUMAN,
B7ZKN7_HUMAN
UniprotKB:
P54132,
H0YNU5,
B7ZKN7
UniParc:
UPI000189A7B5,
UPI00022F876E,
UPI00001269FA
EMBL:
U39817,
KF511223,
BC101567,
AY886902,
BC115030,
AC124248,
BC115032,
BC093622,
BC143280,
AC021422
Ensembl:
ENSG00000197299
KO:
hsa:641
|
| Nucleutide sequences |
EMBL-CDS:
AAI15031.1,
AAW62255.1,
AAI15033.1,
AAA87850.1,
AAH93622.1,
AAI01568.1,
AAI43281.1
Ensembl_TRS:
ENST00000355112,
ENST00000560509
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347232,
ENSP00000454158
RefSeq:
NP_000048.1,
NP_001274175.1,
XP_006720695.1,
NP_001274176.1,
XP_011520184.1,
NP_001274177.1,
XP_011520183.1
|
| Others |
UniRef100:
UniRef100_H0YNU5,
UniRef100_P54132,
UniRef100_B7ZKN7
UniRef90:
UniRef90_P54132,
UniRef90_G3QXK2,
UniRef90_B7ZKN7
UniRef50:
UniRef50_F7CZ93,
UniRef50_P54132
UniGene:
Hs.725208
CCDS:
CCDS10363.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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