Type | Description |
---|---|
Definition | neuronal PAS domain protein 3 |
Date | Results | Publications |
---|---|---|
2019-04-27 12:11:00 | NPAS3 is a true transcription factor capable of regulating expression of target genes through their promoters by directly cooperating with ARNT. | 30509165 |
2018-04-07 11:22:00 | Study provides a clear, unbiased view of the full spectrum of genes regulated by NPAS1 and NPAS3 and shows that these transcription factors are master regulators of neuropsychiatric function. These findings expose the molecular pathophysiology of NPAS1/3 mutations and provide a striking example of the shared, combinatorial nature of molecular pathways that underlie diagnostically distinct neuropsychiatric conditions. | 28499489 |
2017-12-16 11:02:00 | Here the authors examined the crystal structures of multi-domain NPAS1-ARNT and NPAS3-ARNT-DNA complexes, discovering each to contain four putative ligand-binding pockets. | 27782878 |
2016-06-28 10:28:00 | Authors hypothesize that any nucleotide variant at the NPAS3 HAEs may lead to altered susceptibility to schizophrenia. | 25982957 |
2014-08-30 12:35:00 | Identification of NPAS3-V304I helps strengthen the hypothesis that NPAS3 is involved in schizophrenia pathogenesis | 23337948 |
Type | IDs |
---|---|
Synonymous | MOP6, PASD6, bHLHe12 |
Gene |
UniProtKB-ID:
NPAS3_HUMAN,
X5D7M0_HUMAN,
X5D988_HUMAN,
X5D2Q4_HUMAN
UniprotKB:
Q8IXF0,
X5D7M0,
X5D988,
X5D2Q4
UniParc:
UPI0000073AA2,
UPI00002264B9,
UPI00000743C2,
UPI0000190F7B,
UPI0004437E96,
UPI00000743C0,
UPI0000070169
EMBL:
AY157302,
AY157303,
KJ534898,
AB054576,
AB055962,
KJ534895,
AL079281,
KJ534894,
AB054575,
AF164438
Ensembl:
ENSG00000151322
KO:
hsa:64067
|
Nucleutide sequences |
EMBL-CDS:
BAB21221.1,
BAC53756.1,
AAO17044.1,
BAC53754.1,
AAG35180.1,
CAB45154.1,
AAO17043.1,
AHW56535.1,
AHW56538.1,
AHW56534.1
Ensembl_TRS:
ENST00000357798,
ENST00000356141,
ENST00000548645,
ENST00000547068,
ENST00000346562
|
Protein sequencees |
Ensembl_PRO:
ENSP00000350446,
ENSP00000319610,
ENSP00000449542,
ENSP00000348460,
ENSP00000448916
RefSeq:
XP_016877076.1,
XP_016877074.1,
XP_016877071.1,
XP_005268049.2,
XP_005268048.2,
XP_011535374.1,
XP_011535371.2,
NP_071406.1,
XP_011535373.2,
NP_775182.1,
NP_001158221.1,
XP_016877075.1,
XP_011535369.1,
XP_016877072.1,
NP_001159365.1,
XP_011535372.1,
XP_016877077.1,
XP_016877073.1
|
Others |
UniRef100:
UniRef100_Q8IXF0-2,
UniRef100_X5D7M0,
UniRef100_Q8IXF0
UniRef90:
UniRef90_Q9QZQ0,
UniRef90_Q8IXF0-3
UniRef50:
UniRef50_Q9QZQ0,
UniRef50_Q8IXF0-3
UniGene:
Hs.657892,
Hs.675437,
Hs.675475
CCDS:
CCDS55912.1,
CCDS9645.1,
CCDS53892.1,
CCDS53891.1
|