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64051 Sv2a

64051

Sv2a

synaptic vesicle glycoprotein 2 a

protein-coding

Mus musculus

基因描述

Type Description
Definition synaptic vesicle glycoprotein 2 a

研究结论

Date Results Publications
2020-10-24 14:07:00 An Epilepsy-Associated SV2A Mutation Disrupts Synaptotagmin-1 Expression and Activity-Dependent Trafficking. 32341095
2015-04-18 11:48:00 This study reveals fundamental details of how phosphorylation of Thr84 on SV2A controls its interaction with synaptotagmin-1 and implicates SV2A as a phospho-dependent chaperone 25673844
2014-04-12 10:36:00 observed alterations of SV2A expression in hippocampus are consistent with the hypothesis that SV2A absence favors epileptic seizures around postnatal day 7 23937191
2013-04-13 11:00:00 Action potential- and Ca(2+) -dependent glutamatergic & GABAergic synaptic transmission are differentially altered in the hippocampus of SV2A-deficient mice, but the mechanism of exocytosis itself is not changed. 22847229
2013-01-05 10:54:00 Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles. 22908222

名称对应

Type IDs
Synonymous AI746429, mKIAA0736
Gene
UniProtKB-ID: SV2A_MOUSE
UniprotKB: Q9JIS5
UniParc: UPI000000BA37
EMBL: AK122360, BC046587, BC026494, AF196780, AK028318, AF196781
Ensembl: ENSMUSG00000038486
KO: mmu:64051
Nucleutide sequences
EMBL-CDS: AAF87321.1, BAC25876.1, AAH46587.1, BAC65642.3, AAH26494.1
Ensembl_TRS: ENSMUST00000035371
Protein sequencees
Ensembl_PRO: ENSMUSP00000037576
RefSeq: NP_071313.1
Others
UniRef100: UniRef100_Q9JIS5
UniRef90: UniRef90_Q02563
UniRef50: UniRef50_Q02563
UniGene: Mm.491135
CCDS: CCDS17631.1

全选

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研究热度

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