| Type | Description |
|---|---|
| Definition | spectrin repeat containing, nuclear envelope 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 11:54:00 | In agreement with the association of Nesprin1alpha with photoreceptor ciliary rootlets and the functional interaction between rootletin and Nesprin1 in fibroblasts, the authors demonstrate that multiple isoforms of Nesprin1 are integral components of ciliary rootlets of multiciliated ependymal and tracheal cells. | 28625779 |
| 2018-08-04 10:51:00 | Nesprin-1alpha recruits Akap450 to the nuclear envelope (NE)independently of kinesin and that Akap450, but not other centrosomal proteins, is required for microtubule nucleation from the NE. | 28966089 |
| 2017-09-16 12:23:00 | Nesprin 1alpha2, which lacks actin-binding domains, was crucial for postnatal viability, nuclear positioning, and skeletal muscle function. | 28533284 |
| 2017-08-05 10:56:00 | the positioning of nuclei requires PCM-1, a protein of the centrosome that relocalizes to the nuclear envelope at the onset of differentiation in a manner that is dependent on the presence of nesprin-1. | 27802164 |
| 2016-04-02 10:57:00 | Results suggest that the loss of function of KASH-LESS variant of Nesprin1 giant resulting from Nesprin1 nonsense mutations underlies the molecular etiology of autosomal recessive cerebellar ataxia Type I. | 25843669 |
| Type | IDs |
|---|---|
| Synonymous | 8B, A330049M09Rik, BE692247, C130039F11Rik, CPG2, KASH1, Myne1, mKIAA1756, myne-1 |
| Gene |
UniProtKB-ID:
SYNE1_MOUSE,
Q6ZWR1_MOUSE,
Q80T95_MOUSE,
A0A1L1STC6_MOUSE,
Q0VGB8_MOUSE,
Q6PI72_MOUSE,
Q7TQH5_MOUSE,
Q6ZWR5_MOUSE
UniprotKB:
Q6ZWR6,
Q6ZWR1,
Q80T95,
A0A1L1STC6,
Q0VGB8,
Q6PI72,
Q7TQH5,
Q6ZWR5
UniParc:
UPI0008FC1CBA,
UPI000000405D,
UPI000000401B,
UPI00001B05E2,
UPI0000D8B938,
UPI0000DBE1AA,
UPI00003B0F2E,
UPI000000B255,
UPI0000003FFC,
UPI0001C67AAE,
UPI0000D63306
EMBL:
AF281870,
AF281869,
AC156393,
AK039486,
AK044459,
AC156392,
AC162381,
BC054456,
AC162385,
BC041779,
AC157020,
AC159748,
AC161829,
AK036828,
BC110428,
AF535143,
AK122550
Ensembl:
ENSMUSG00000096054
KO:
mmu:64009
|
| Nucleutide sequences |
EMBL-CDS:
AAG24393.1,
BAC29595.1,
AAG24392.1,
AAN03487.1,
BAC31932.1,
BAC65832.2,
AAI10429.1,
AAH41779.1,
AAH54456.1,
BAC30365.1
Ensembl_TRS:
ENSMUST00000095899,
ENSMUST00000041639,
ENSMUST00000215295,
ENSMUST00000214945
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039440,
ENSMUSP00000093587,
ENSMUSP00000150262,
ENSMUSP00000149011
RefSeq:
XP_030101064.1,
XP_036011817.1,
NP_071310.2,
XP_036011827.1,
XP_017169533.1,
NP_001334640.1,
XP_036011830.1,
NP_001073154.1,
XP_036011805.1,
XP_036011813.1,
XP_036011828.1,
XP_036011819.1,
XP_036011807.1,
XP_036011810.1,
XP_036011812.1,
XP_036011824.1,
XP_036011825.1,
XP_011241388.1,
XP_036011822.1,
XP_036011809.1,
XP_036011816.1,
XP_036011829.1,
NP_700448.2,
XP_036011818.1,
XP_036011814.1,
XP_036011808.1,
XP_036011806.1,
XP_036011820.1,
XP_036011815.1,
XP_036011811.1,
XP_036011823.1,
XP_036011826.1,
NP_001334661.1,
XP_036011831.1,
XP_036011821.1
|
| Others |
UniRef100:
UniRef100_A0A1L1STC6,
UniRef100_Q6ZWR6,
UniRef100_Q7TQH5,
UniRef100_Q6ZWR5,
UniRef100_Q6ZWR1,
UniRef100_Q6PI72,
UniRef100_Q0VGB8,
UniRef100_Q6ZWS6
UniRef90:
UniRef90_Q6ZWR1,
UniRef90_A0A1L1STC6,
UniRef90_Q0VGB8,
UniRef90_Q6ZWS6,
UniRef90_Q6ZWR6,
UniRef90_A0A5P8DHN0
UniRef50:
UniRef50_Q6ZWR1,
UniRef50_Q6ZWS6,
UniRef50_Q8NF91,
UniRef50_Q8NF91-9
UniGene:
Mm.331626
CCDS:
CCDS56679.1,
CCDS56680.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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