| Type | Description |
|---|---|
| Definition | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Sel1L-Hrd1 ER-associated degradation maintains beta cell identity via TGF-beta signaling. | 32182217 |
| 2020-09-19 16:27:00 | Narrowing down the Common Cytogenetic Deletion 14q to a 5.6-Mb Critical Region in 1p/19q Codeletion Oligodendroglioma-Relapsed Patients Points to Two Potential Relapse-Related Genes: SEL1L and STON2. | 32575107 |
| 2019-06-15 12:14:00 | we found key statistical differences for the proteins SEL1, Notch3 and SOCS3 in the progression of uterine cervical cancer | 29532409 |
| 2018-12-01 10:12:00 | In summary, ER retention of pathogenic VLDLR mutants involves binding to calnexin, elevated endoplasmic reticulum stress, and delayed degradation which is dependent on SEL1L. | 29371607 |
| 2018-09-15 11:18:00 | Silencing of SEL1L during infection also stabilized an interaction of gO with the ER lectin OS-9, which likewise suggests that gO is an ER-associated degradation (ERAD) substrate. Taken together, our results identify an intriguing interaction of UL148 with the ERAD machinery and demonstrate that gO behaves as a constitutive ERAD substrate during infection. | 29997207 |
| Type | IDs |
|---|---|
| Synonymous | Hrd3, PRO1063, SEL1-LIKE, SEL1L1 |
| Gene |
UniProtKB-ID:
SE1L1_HUMAN,
Q3ZCU6_HUMAN
UniprotKB:
Q9UBV2,
Q3ZCU6
UniParc:
UPI0000135746,
UPI00000389D2,
UPI00005AB2C4
EMBL:
AF198647,
AB024763,
AF198643,
AF198640,
BC040498,
AF198637,
AF198634,
AF198642,
AF198638,
AF052059,
AF198631,
AF198636,
AF198644,
AF198641,
AF198639,
AY358651,
AB020335,
AF198635,
AF198646,
AF198632,
AF198645,
AF198633,
AF157516
Ensembl:
ENSG00000071537
KO:
hsa:6400
|
| Nucleutide sequences |
EMBL-CDS:
AAF24176.1,
AAF29413.1,
BAA89204.1,
AAQ89014.1,
BAA87904.1,
AAL40905.1,
AAH40498.1
Gene_ORFName:
UNQ128/PRO1063
Ensembl_TRS:
ENST00000336735,
ENST00000555824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000450709,
ENSP00000337053
RefSeq:
NP_001231913.1,
XP_005268045.1,
NP_005056.3,
XP_005268046.1
|
| Others |
UniRef100:
UniRef100_Q3ZCU6,
UniRef100_Q9UBV2
UniRef90:
UniRef90_Q9UBV2,
UniRef90_Q3ZCU6
UniRef50:
UniRef50_Q3ZCU6,
UniRef50_Q9UBV2
UniGene:
Hs.181300
CCDS:
CCDS58333.1,
CCDS9876.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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