| Type | Description |
|---|---|
| Definition | CDK5 and Abl enzyme substrate 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:35:00 | Overexpression and short hairpin RNA-mediated depletion of CABLES1 protein resulted in p21(Cip/waf) up- and down-regulation. Aged mice lacking Cables1 displayed abnormalities in peripheral blood cell counts accompanied by a significant reduction in hematopoietic stem cells compartment, concomitant with an increased mobilization of progenitor cells. | 31327733 |
| 2014-05-03 10:52:00 | Loss of Cables1 enhances tumor progression in the Apc(Min/+) mouse model and activates the Wnt/beta-catenin signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model. | 23792637 |
| 2014-04-26 12:14:00 | Agenesis of the corpus callosum frequency in Cables1(+/TAS) mice was significantly lower than that in Cables1(-/TAS) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS). | 24336072 |
| 2010-10-30 11:14:00 | Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress. | 20559324 |
| 2010-01-21 00:00:00 | Loss or suppression of Cables may be an early step in the development of endometrial cancer. | 14729625 |
| Type | IDs |
|---|---|
| Synonymous | Cables, ik3-1 |
| Gene |
UniProtKB-ID:
CABL1_MOUSE,
Q3U148_MOUSE,
Q3TYS6_MOUSE
UniprotKB:
Q9ESJ1,
Q3U148,
Q3TYS6
UniParc:
UPI00005AD1CA,
UPI00005ACFE3,
UPI0000026608
EMBL:
AK158396,
AK156273,
AF133208,
AC100751,
AF328140,
AC132941
Ensembl:
ENSMUSG00000040957
KO:
mmu:63955
|
| Nucleutide sequences |
EMBL-CDS:
AAG33933.1,
AAG42916.1,
BAE33652.1,
BAE34486.1
Ensembl_TRS:
ENSMUST00000046948,
ENSMUST00000171109
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040639,
ENSMUSP00000129463
RefSeq:
NP_071304.2,
NP_001139759.1
|
| Others |
UniRef100:
UniRef100_Q9ESJ1,
UniRef100_Q3TYS6,
UniRef100_Q3U148
UniRef90:
UniRef90_Q9ESJ1
UniRef50:
UniRef50_Q9ESJ1
UniGene:
Mm.40717
CCDS:
CCDS29061.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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