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63943 FKBPL

63943

FKBPL

FKBP prolyl isomerase like

protein-coding

Homo sapiens

基因描述

Type Description
Definition FKBP prolyl isomerase like

研究结论

Date Results Publications
2017-09-02 13:45:00 This study identified two low-frequency nonsynonymous variants at FKBPL (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk. 27479355
2016-04-09 10:37:00 The data suggests a role for FKBPL as a prognostic factor for BCSS, with the potential to be routinely evaluated within the clinic. 25906750
2015-06-20 11:28:00 WISp39 preferentially interacts with phosphorylated Coronin 1B, allowing it to complex with Slingshot phosphatase to dephosphorylate and activate Cofilin. 25800056
2015-06-06 10:09:00 FKBPL is an important regulator of developmental and pathological angiogenesis. 25767277
2014-08-30 10:52:00 high levels of FKBPL and RBCK1 correlated with increased patient survival, whereas high RBCK1 predicted for a poor response to tamoxifen. 23912458

名称对应

Type IDs
Synonymous DIR1, FKBP4, NG7, WISP39
Gene
UniProtKB-ID: FKBPL_HUMAN, A0A024RCQ6_HUMAN
UniprotKB: Q9UIM3, A0A024RCQ6
UniParc: UPI0000036B85
EMBL: KY500325, CH471081, AL662828, CR457374, BC004168, AK291418, U89337, AL662884, CR925796, CR753803, AK027119, BC011966, AF139374
Ensembl: ENSG00000224200, ENSG00000223666, ENSG00000230907, ENSG00000204315
KO: hsa:63943
Nucleutide sequences
EMBL-CDS: AAF04864.1, AAF67785.1, BAB15663.1, BAF84107.1, CAG33655.1, AAH11966.1, AAH04168.1, EAX03586.1, AQY76813.1, EAX03587.1
Gene_ORFName: hCG_1643117
Ensembl_TRS: ENST00000443350, ENST00000375156, ENST00000456854, ENST00000425378
Protein sequencees
Ensembl_PRO: ENSP00000412439, ENSP00000364298, ENSP00000398812, ENSP00000397530
RefSeq: NP_071393.2
Others
UniRef100: UniRef100_Q9UIM3
UniRef90: UniRef90_Q9UIM3
UniRef50: UniRef50_Q9UIM3
UniGene: Hs.520042
CCDS: CCDS4738.1

全选

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