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63940 GPSM3

63940

GPSM3

G protein signaling modulator 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein signaling modulator 3

研究结论

Date Results Publications
2017-05-20 14:20:00 role for GPSM3 in neutrophil migration toward proinflammatory chemoattractants LTB4 and CXCL8-a discovery that helps strengthen the association between the promoter-weakening GPSM3 SNP rs204989 and a reduced risk of rheumatoid arthritis 27307211
2016-12-17 11:56:00 Genetic variations in GPSM3 which are associated with protection from rheumatoid arthritis affect its transcript abundance. 26821282
2015-02-14 12:53:00 findings suggest that GPSM3 acts as a direct negative regulator of NLRP3 function. 25271165
2012-11-24 11:00:00 Phosphorylation of GPSM3 by a proline-directed serine/threonine kinase and the resultant association of 14-3-3 is the first description of post-translational regulation of GPSM3 subcellular localization 22843681
2012-04-21 12:02:00 GPSM3 increases Gbeta stability until formation of the Gbetagamma dimer, including association of the Gbeta-GPSM3 complex with phosducin-like protein PhLP and T-complex protein 1 subunit eta (CCT7), two known chaperones of neosynthesized Gbeta subunits. 22167191

名称对应

Type IDs
Synonymous AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1
Gene
UniProtKB-ID: GPSM3_HUMAN, A0A024RCP6_HUMAN
UniprotKB: Q9Y4H4, A0A024RCP6
UniParc: UPI0000073FDF
EMBL: BX927239, KY500354, KY500352, AF155657, AL662830, AL845464, BC018724, AL662884, CR933878, CR812478, AJ243937, BX284686, CH471081, KY500353, AK313922
Ensembl: ENSG00000206314, ENSG00000236697, ENSG00000213654, ENSG00000237052, ENSG00000233490, ENSG00000234243, ENSG00000234508
KO: hsa:63940
Nucleutide sequences
EMBL-CDS: AAH18724.1, AAF67476.1, EAX03620.1, CAB51288.1, BAG36643.1, AQY76839.1, EAX03623.1, AQY76840.1, AQY76841.1
Gene_ORFName: hCG_2044638
Ensembl_TRS: ENST00000420041, ENST00000432871, ENST00000448684, ENST00000383265, ENST00000424520, ENST00000429209, ENST00000375040, ENST00000441705, ENST00000375043, ENST00000457070, ENST00000414839, ENST00000445326, ENST00000383269, ENST00000453667
Protein sequencees
Ensembl_PRO: ENSP00000396786, ENSP00000410087, ENSP00000413430, ENSP00000414024, ENSP00000405026, ENSP00000403132, ENSP00000364180, ENSP00000407538, ENSP00000413975, ENSP00000372756, ENSP00000392487, ENSP00000414939, ENSP00000372752, ENSP00000364183
RefSeq: NP_071390.1, NP_001263430.1
Others
UniRef100: UniRef100_Q9Y4H4
UniRef90: UniRef90_Q9Y4H4
UniRef50: UniRef50_Q9Y4H4
UniGene: Hs.520046
CCDS: CCDS34419.1

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