| Type | Description |
|---|---|
| Definition | PDX1 C-terminal inhibiting factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-11 16:33:00 | PCIF1 depletion leads to loss of m6Am RNA modification from the transcriptional-start-sites of mRNAs | 31822664 |
| 2020-03-07 10:19:00 | The authors identified, characterized biochemical property and substrate preference of PCIF1 as "stand-alone" RNA methyltransferase and proposed a model for mammalian mRNA m6Am modification mediated by PCIF1. | 30487554 |
| 2020-01-18 10:43:00 | we identify the only human mRNA m6Am methyltransferase and demonstrate a mechanism of gene expression regulation through PCIF1-mediated m6Am mRNA methylation. | 31279659 |
| 2020-01-18 10:43:00 | We find that depleting PCIF1 does not substantially affect mRNA translation but is associated with reduced stability of a subset of m(6)Am-annotated mRNAs. The discovery of PCIF1 and our accurate mapping technique will facilitate future studies to characterize m(6)Am's function. | 31279658 |
| 2019-08-03 11:21:00 | PCIF1/CAPAM (cap-specific adenosine methyltransferase) is a cap-specific N (6)-methyladenosine writer for mRNAs | 30467178 |
| Type | IDs |
|---|---|
| Synonymous | C20orf67, CAPAM, PPP1R121, hCAPAM, hPCIF1 |
| Gene |
UniProtKB-ID:
CAPAM_HUMAN
UniprotKB:
Q9H4Z3
UniParc:
UPI000000D717
EMBL:
AB050014,
AL137473,
CH471077,
BC013365,
AL162458,
BC010005
Ensembl:
ENSG00000100982
KO:
hsa:63935
|
| Nucleutide sequences |
EMBL-CDS:
EAW75778.1,
AAH10005.1,
CAB70757.2,
AAH13365.1,
BAC45238.1,
EAW75780.1
Ensembl_TRS:
ENST00000372409
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361486
RefSeq:
XP_011527283.1,
XP_011527282.1,
NP_071387.1,
XP_016883503.1,
XP_016883502.1
|
| Others |
UniRef100:
UniRef100_Q9H4Z3
UniRef90:
UniRef90_Q9H4Z3
UniRef50:
UniRef50_Q9H4Z3
UniGene:
Hs.472856
CCDS:
CCDS13388.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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