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63929 XPNPEP3

63929

XPNPEP3

X-prolyl aminopeptidase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition X-prolyl aminopeptidase 3

研究结论

Date Results Publications
2018-09-29 12:22:00 results therefore suggest XPNPEP3 to be a transcriptional target of Wnt/beta-catenin pathway with particular significance for CRC 29383790
2017-07-08 11:52:00 Data suggest that human XPNPEP3, Ashbya gossypii Icp55, and Fusarium graminearum Icp55 exhibit structural and functional properties of genuine Xaa-Pro specific aminopeptidases; these enzymes appear to function in the previously observed mitochondrial role of Icp55 in processing of Nfs1 (mitochondrial cysteine desulfurase) substrate. [Icp55 = intermediate-cleavage metalloexopeptidases 55] 28476889
2016-04-02 11:21:00 The findings reveal that APP3m is a new member of the TNF-TNFR2 signaling complex and characterize an APP3-mediated TNFR2 signal transduction mechanism that induces activation of JNK1 and JNK2. 25609706
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 21068128
2010-04-12 11:37:00 Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. 20179356

名称对应

Type IDs
Synonymous APP3, ICP55, NPHPL1
Gene
UniProtKB-ID: XPP3_HUMAN, A0A087X0Z2_HUMAN
UniprotKB: Q9NQH7, A0A087X0Z2
UniParc: UPI00000714C6, UPI00000401EA, UPI00000401E0, UPI0000D49188, UPI000191523D, UPI00000401EC
EMBL: AL035450, AL834310, CH471095, AK301758, BC001681, AL365514, CR457396, AK313770, AL080242, BC001208, AK301635, CR456442, BC004989, Z98048
Ensembl: ENSG00000196236
KO: hsa:63929
Nucleutide sequences
EMBL-CDS: EAW60399.1, BAG36508.1, AAH01681.1, CAD38980.1, AAH01208.1, CAG33677.1, CAG30328.1, AAH04989.1, BAH13526.1, BAH13548.1, CAB97210.1, EAW60397.1
Gene_ORFName: hCG_41117
Ensembl_TRS: ENST00000357137, ENST00000614001
Protein sequencees
Ensembl_PRO: ENSP00000349658, ENSP00000483752
RefSeq: NP_001191756.1, NP_071381.1
Others
UniRef100: UniRef100_Q9NQH7, UniRef100_A0A087X0Z2
UniRef90: UniRef90_A0A087X0Z2, UniRef90_Q9NQH7
UniRef50: UniRef50_A0A087X0Z2, UniRef50_Q9NQH7
UniGene: Hs.529163
CCDS: CCDS14007.1

全选

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