| Type | Description |
|---|---|
| Definition | engulfment and cell motility 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:54:00 | Clinical and Molecular Study of ELMO-2-Related Massive Intraosseous Vascular Malformations: Lessons Learned From 25 Years of Follow-up. | 30882408 |
| 2019-02-23 11:02:00 | Study demonstrated that an evolutionarily conserved fragment in the C-terminal cytoplasmic tail of BAI-aGPCRs is specifically recognized by the RBD-ARR-ELMO (RAE) supramodule of the ELMO family scaffolds. The crystal structures of ELMO2-RAE and its complex with BAI1 uncover the molecular basis of BAI/ELMO interactions. | 30604775 |
| 2017-05-20 14:49:00 | These data suggest a novel link between Tiam1 and RhoG/ILK /ELMO2 pathway as upstream effectors of the Rac1-mediated phagocytic process in trabecular meshwork cells. | 27539661 |
| 2017-05-13 22:31:00 | studies demonstrate that Elmo2 is a new regulator of insulin-dependent Glut4 membrane translocation through modulating Rac1 activity and Akt membrane compartmentalization. | 27226625 |
| 2017-05-13 10:45:00 | findings highlight the necessity of ELMO2 for maintaining vascular integrity, specifically in intramembranous bones; loss-of-function mutations in ELMO2 cause intraosseous vascular malformation by impeding RAC1 signaling | 27476657 |
| Type | IDs |
|---|---|
| Synonymous | CED-12, CED12, Ced-12A, ELMO-2, VMPI |
| Gene |
UniProtKB-ID:
ELMO2_HUMAN
UniprotKB:
Q96JJ3
UniParc:
UPI000013F6C4,
UPI00001B31C2
EMBL:
AL031686,
AK057032,
BC000143,
AL133227,
CH471077,
AK023103,
AF417861,
AB058737,
AF398886,
AK022731,
AK021718
Ensembl:
ENSG00000062598
KO:
hsa:63916
|
| Nucleutide sequences |
EMBL-CDS:
BAB14405.1,
BAB47463.1,
EAW75746.1,
EAW75743.1,
AAL14467.1,
AAL38512.1,
EAW75739.1,
AAH00143.2,
EAW75745.1,
BAB14210.1,
BAB13879.1,
BAB71350.1
Ensembl_TRS:
ENST00000396391,
ENST00000372176,
ENST00000290246
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361249,
ENSP00000379673,
ENSP00000290246
RefSeq:
XP_016883498.1,
XP_005260558.1,
XP_005260553.1,
XP_006723917.1,
XP_016883500.1,
XP_005260555.1,
NP_001305182.1,
XP_024307729.1,
XP_005260556.1,
NP_573403.1,
NP_877496.1,
XP_016883499.1,
XP_005260557.1
|
| Others |
UniRef100:
UniRef100_Q96JJ3
UniRef90:
UniRef90_Q96JJ3
UniRef50:
UniRef50_Q96JJ3
UniGene:
Hs.210469
CCDS:
CCDS13398.1,
CCDS82623.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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