Type | Description |
---|---|
Definition | ubiquitin conjugating enzyme E2 O |
Date | Results | Publications |
---|---|---|
2021-02-02 13:25:00 | Saliva exosomes-derived UBE2O mRNA promotes angiogenesis in cutaneous wounds by targeting SMAD6. | 32375794 |
2021-01-16 15:57:00 | UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKalpha2/mTORC1-MYC positive feedback loop. | 31907353 |
2020-07-25 12:03:00 | Study found that UBE2O is markedly upregulated in obese subjects with type 2 diabetes. | 31292296 |
2020-05-09 12:57:00 | UBE2O directly mediates the ubiquitination of many substrates, including AMPKalpha2, BAP1, MLL protein SMAD6, c-Maf, ARNTL, and free ribosomal proteins. UBE2O is frequently amplified or mutated in multiple cancers, and its high expression is associated with low survival rate of gastric, lung, breast, and prostate cancer patients. Review. | 30468556 |
2019-05-04 10:08:00 | UBE2O is critical for P-TEFb recruitment to the HIV-1 promoter. | 29845934 |
Type | IDs |
---|---|
Synonymous | E2-230K |
Gene |
UniProtKB-ID:
UBE2O_HUMAN
UniprotKB:
Q9C0C9
UniParc:
UPI000020032F
EMBL:
AL832432,
BC036820,
AK025999,
BC004525,
AB051521,
CH471099,
AK022940,
BC025977,
BC051868,
AK024657,
AC090699,
BC022237
Ensembl:
ENSG00000175931
KO:
hsa:63893
|
Nucleutide sequences |
EMBL-CDS:
BAB14948.1,
AAH36820.1,
BAB14320.1,
BAB21825.1,
AAH04525.2,
CAH10644.1,
EAW89396.1,
BAB15313.1,
AAH25977.1,
AAH22237.1,
AAH51868.2
Ensembl_TRS:
ENST00000319380
|
Protein sequencees |
Ensembl_PRO:
ENSP00000323687
RefSeq:
XP_024306633.1,
XP_005257624.1,
NP_071349.3,
XP_016880424.1,
XP_024306635.1,
XP_024306634.1
|
Others |
UniRef100:
UniRef100_Q9C0C9
UniRef90:
UniRef90_Q9C0C9
UniRef50:
UniRef50_Q9C0C9
UniGene:
Hs.16130
CCDS:
CCDS32742.1
|
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